Results 61 to 70 of about 2,313,139 (293)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

La primavera de la animación en series 2D

open access: yesCon A de Animación, 2018
La animación 2D para televisión es uno de los contenidos que nos han acompañado a lo largo de los años. Los estudios Hanna-Barbera se encargaron de buscar un sistema de producción rentable para poder llevar a cabo más de 200 series diferentes.
Sergio Rodríguez Valdunciel
doaj   +1 more source

Gate controlled valley polarizer in bilayer graphene

open access: yesNature Communications, 2020
Here, the authors present a gate-controlled valley-polarizer based on bilayer graphene, and through optimized device geometry and stacking method they obtain two orders of magnitude difference in conductance between the valley-polarized state and gapped ...
Hao Chen   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Evaluation of Advanced Bimanual Skills in Novices Using the Wrist-Like FlexDex™ Articulating Laparoscopic Needle Holder in 2D and 3D Vision: A Randomised Trial

open access: yesMedical Devices: Evidence and Research, 2021
Nima Motahariasl,1 Sayed Borna Farzaneh,1 Sina Motahariasl,2 Ilya Kokotkin,3 Sara Sousi,4,5 Alexander Zargaran,5,6 David Zargaran,7 Bijendra Patel8 1St George’s Hospital NHS Trust, London, SW17 0QT, Greater London, UK; 2Lewisham and Greenwich NHS Trust ...
Motahariasl N   +7 more
doaj  

Arrugas. Un viaje al extranjero, desde el comienzo hasta el final

open access: yesCon A de Animación, 2013
Arrugas, dirigida por Ignacio Ferreras, es uno de los últimos largometrajes de animación 2D de factura "made in Spain" que nos deja disfrutar al público adulto de una historia dura y real, pero mágica.
Pilar Yébenes
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

To infinity and back again: Hand-drawn aesthetic and affection for the past in Pixar's pioneering animation

open access: yesAlphaville: Journal of Film and Screen Media, 2015
In 2011, Pixar Animation Studios released a short film that challenged the contemporary characteristics of digital animation. La Luna (Enrico Casarosa) marks a pivotal shift in Pixar's short film canon by displaying hand-drawn artwork and man-made ...
Helen Haswell
doaj   +1 more source

Topological phase singularities in atomically thin high-refractive-index materials

open access: yesNature Communications, 2022
The authors combine films of two-dimensional semiconductors, which exhibit excitonic spectral features, with SiO2/Si Fabry-Perot resonators in order to realize topological phase singularities in reflection.
Georgy Ermolaev   +17 more
doaj   +1 more source

Perspectives of 2D MXene Tribology

open access: yesAdvances in Materials, 2022
The large and rapidly growing family of 2D early transition metal carbides, nitrides, and carbonitrides (MXenes) raises significant interest in the materials science and chemistry of materials communities.
A. Rosenkranz   +4 more
semanticscholar   +1 more source

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