Results 141 to 150 of about 802,182 (218)

Advanced imaging and multi‐omics to characterize cardiomyocyte ageing and its electrocardiographic imprint in PKP2 arrhythmogenic cardiomyopathy

The Journal of Physiology, EarlyView.
Abstract figure legend We used a murine model of cardiomyocyte‐specific conditional knockout of plakophilin 2 (PKP2cKO, middle panel). Using advanced imaging technology, we unveiled distinct hallmarks of premature ageing in PKP2cKO cardiomyocytes, including DNA damage and loss of repressed heterochromatin at the nuclear periphery, and mitochondrial ...
Giorgia Bertoli, Kavya Phadke, Alessandro Cospito, Xianming Lin, Marina Cerrone, Joanna Abi Rizk, Michael Cammer, Yan Deng, Joseph Sall, Mingliang Zhang, Feng‐Xia Liang, Irene de Lázaro, Mario Delmar   +12 more
wiley   +1 more source

Multiscale four‐dimensional imaging of cardiac remodelling after myocardial infarction

The Journal of Physiology, EarlyView.
Abstract figure legend Multiscale 4D imaging framework for integrated phenotyping of post‐infarction remodelling. Myocardial infarction triggers dynamic changes across mechanical, haemodynamic and biological axes, progressing from acute injury and inflammation to extracellular matrix remodelling and scar maturation.
Hanzhou Lei, Boris Martinac, Yang Guo
wiley   +1 more source

Asymptomatic Cardiotoxicity After High‐Dose Anthracycline Treatment in Sarcoma Patients Assessed by Biomarkers and Echocardiography

International Journal of Cancer, Volume 159, Issue 11, Page 2755-2765, 1 December 2026.
ABSTRACT Treatment of sarcoma includes high‐dose anthracyclines, which can cause cardiotoxicity. This study assesses the correlation of cardiac biomarkers and echocardiographic parameters on asymptomatic cardiotoxicity in sarcoma patients treated with anthracyclines.
Elissa A. S. Polomski, Frank M. Speetjens, J. Wouter Jukema, Julius C. Heemelaar, Michiel A. J. van de Sande, Hans Gelderblom, M. Louisa Antoni   +6 more
wiley   +1 more source

Prognostic utility of quantitative offline 2D-echocardiography in hospitalized patients with COVID-19 disease. [PDF]

Echocardiography, 2020
Bursi F, Santangelo G, Sansalone D, Valli F, Vella AM, Toriello F, Barbieri A, Carugo S.   +7 more
europepmc   +1 more source

Chios Mastic in Well‐Controlled Hypertension: Findings From the HYPER‐MASTIC Randomized Controlled Trial

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Residual cardiovascular risk persists in patients with adequately controlled hypertension, driven partly by inflammation, oxidative stress and endothelial dysfunction. Chios mastic (Pistacia lentiscus var. Chia) has shown antihypertensive, antioxidant and vascular effects in experimental and clinical settings.
Ioanna Panagiota Kalafati, Anastasia‐Areti Kyriazopoulou‐Korovesi, Evangelia Mentsiou‐Nikolaou, Maria Papaioannou, Christina Konstantaki, Lasthenis Angelidakis, Despoina D. Gianniou, Eleni V. Mikropoulou, Panagiota Giardoglou, Dimitrios Valakos, Giannis Vatsellas, HYPER‐MASTIC Consortium, Ioanna Andreadou, Efstathios Manios, Maria Halabalaki, Ioannis P. Trougakos, George V. Dedoussis, Kimon Stamatelopoulos   +17 more
wiley   +1 more source

Effects of community-acquired pneumonia on biventricular cardiac functions in children

Italian Journal of Pediatrics
Background This study aimed to evaluate the effects of community-acquired pneumonia (CAP) on cardiac function in children and compare the effectiveness of tissue Doppler imaging (TDI) and two-dimensional speckle tracking echocardiography (2D-STE) with ...
Rehab Elmeazawy, Esraa Abd Al-Fattah Sorour, Al Shimaa Badreldeen   +2 more
doaj   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, Volume 200, Issue 11, Page 2568-2574, November 2026.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

Hyperdominant Left Circumflex Artery Challenging Conventional Paradigms and Current Guideline Recommendations: A Comprehensive Literature Review and Case Series

Clinical Case Reports, Volume 14, Issue 11, November 2026.
Summary of the patient's presentation, diagnostic evaluation, treatment, and follow‐up. ABSTRACT Despite its rarity in the general population, left dominant coronary circulation with a hyperdominant left circumflex artery (LCx) has been associated with a more severe risk for ischemic and coronary artery disease. The concealment of an isolated posterior
Amirmahdi Mohammadi, Mohammad Sadegh‐Vashveshady   +1 more
wiley   +1 more source

Right Ventricular Dysfunction and Ventriculo‐Arterial Uncoupling in Heart Failure With Preserved Ejection Fraction: A Phenotype‐Specific Review of Mechanisms, Diagnosis, and Therapeutic Strategies

Clinical Cardiology, Volume 49, Issue 11, November 2026.
Right ventricular dysfunction affects 19%–33% of patients With heart failure With preserved ejection fraction and is associated With exercise intolerance, hospitalization, and mortality. Assessing right ventricular function and its coupling with the pulmonary circulation may improve risk stratification and support management tailored to distinct ...
Amarelle Chamoun, Talha Farooq, Suhayya Batool, Sadia Tameez‐ud—din, Muhammad Yousaf, Preet Memon, Mohsin Ali, Arun Kumar Maloth, F. N. U. Sawaira, Muhammad Taimur Khan, Mohammad Eisa Ali, Mansoor Khalid, Maleeha Pandit, Kamil Ahmad Kamil   +13 more
wiley   +1 more source

Baseline LV ejection fraction by cardiac magnetic resonance and 2D echocardiography after ST-elevation myocardial infarction - influence of infarct location and prognostic impact. [PDF]

Eur Radiol, 2020
Schwaiger JP, Reinstadler SJ, Tiller C, Holzknecht M, Reindl M, Mayr A, Graziadei I, Müller S, Metzler B, Klug G.   +9 more
europepmc   +1 more source