Results 181 to 190 of about 296,091 (248)

2g. Freemium Open Access

, 2017
openaire   +1 more source

Triazole-Functionalized Jatrophone Derivatives as Antiprotozoal Agents Against <i>Trypanosoma cruzi</i>: Synthesis, Biological Evaluation and Structure-Activity Relationships. [PDF]

Pharmaceuticals (Basel)
Pertino MW, Carreño Gonzalez P, Venegas González C, Schmeda-Hirschmann G, Vega Gómez C, Rolón M, Rojas de Arias A.   +6 more
europepmc   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

Development of Colonic Polyposis in a Woman With Chronic Myeloid Leukemia Treated With Dasatinib. [PDF]

Case Rep Hematol
Pelaez G, Yildiz BS, Candan M, Ismail M, Vacca F, Ruzinova MB, Ballentine S, Byrnes K, Ghobadi A.   +8 more
europepmc   +1 more source

Integrated Visible Light and Oxidant Protection Through Multifunctional Sunscreens

Advanced Healthcare Materials, EarlyView.
High‐energy visible radiation (HEVR), although less energetic than UV light, penetrates deeper into the skin and contributes to photoaging, pigmentation disorders, and oxidative stress. The development of new HEVR‐targeted filters, therefore, represents not only a scientific challenge but also a pressing public health and cosmetic industry need.
Beatriz Peñín, Raúl Losantos, Ignacio Funes‐Ardoiz, Diego Sampedro   +3 more
wiley   +1 more source

Case Report: Nutrition profile, body mass, sleep quality, and acute mountain sickness symptoms during altitude training in a Paralympic record-breaking athlete and his two guides. [PDF]

Front Nutr
Belluco K, Breda FL, Lourenço TF, Cirino C, Papoti M, Gobatto CA, Manchado-Gobatto FB.   +6 more
europepmc   +1 more source

Fully Wireless and Flexible Valves for Multiplexed and Prolonged Intravesical Liquid Release

Advanced Healthcare Materials, EarlyView.
A fundamental mechanism for the simultaneous control of multiple magnetic valves is reported in a miniature soft robotic patch for intravesical drug delivery, enabling fully wireless and programmable liquid release. Integrated with a bioadhesive interface and induction‐coupling‐based liquid volume sensing, the soft robotic patch is promising to enable ...
Boyang Xiao, Yi Zhu, Yusheng Wang, Janene M. Pierce, Jeffrey J. Tosoian, Xiaoguang Dong   +5 more
wiley   +1 more source

3D‐Printed Piezoionic/Bioelectronic Hydrogel for Electro‐Metabolic Regulation of Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A 3D‐printed piezoionic GPMx hydrogel enables stable electromechanical signal generation under mechanical loading, exhibiting long‐term durability and low fatigue. As a bioactive patch, it restores endogenous bioelectricity to stimulate osteogenesis via Ca2+ influx and mitochondrial activation, while simultaneously enabling label‐free alkaline ...
Sayan Deb Dutta, Myoung Joon Jeon, Youjin Seol, Ki‐Taek Lim   +3 more
wiley   +1 more source

A standardized approach to test missense <i>PNPLA1</i> rare genetic variants of uncertain significance in epidermal differentiation disorders. [PDF]

JID Innov
Pell N, Bernard P, Courrech S, Opalka L, Millán-Sánchez A, Levy E, Garnier S, Clément C, Le Faouder P, Vávrová K, López O, Bertrand-Michel J, Leprince C, Fourquaux I, Mejia JE, Pagès JC, Mazereeuw-Hautier J, Jonca N.   +17 more
europepmc   +1 more source

Long‐Term Hydrophilic, Anti‐Clotting, and Anti‐Fibrotic Dynamic Covalent Silicone‐Based Biomaterials

Advanced Healthcare Materials, EarlyView.
Dynamic covalent crosslinking of a Schiff‐base silicone elastomer with hydrazide‐functionalized polymers is demonstrated to improve the long‐term hydrophilicity as well as the anti‐fouling and anti‐clotting properties of PDMS implants. The hydrazone‐functionalized material prevents hydrophobic recovery, resists clotting, and significantly reduces ...
Norma A. Garza Flores, Eva Mueller, Robert Bui, James C. Fredenburgh, Ruiqi Yin, Rawaa Hussain, Rida A. Malik, Thomas Kalab, Dabeer Abdul‐Azeez, Fei Xu, Michael Brook, Jeffrey I. Weitz, Todd Hoare   +12 more
wiley   +1 more source