Results 311 to 320 of about 19,374,224 (331)
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Harmine prevents 3-nitropropionic acid-induced neurotoxicity in rats via enhancing NRF2-mediated signaling: Involvement of p21 and AMPK.

European Journal of Pharmacology, 2022
Oxidative stress induced neurotoxicity is increasingly perceived as an important neuropathologic mechanism underlying the motor and behavioral phenotypes associated with Huntington's disease (HD). Repeated exposure to 3-nitropropionic acid (3-NP) induces
Mohamed Z. Habib   +8 more
semanticscholar   +1 more source

Erythropoietin and Bacillus Calmette-Guérin Vaccination Mitigate 3-Nitropropionic Acid-Induced Huntington-like Disease in Rats by Modulating the PI3K/Akt/mTOR/P70S6K Pathway and Enhancing the Autophagy.

ACS Chemical Neuroscience, 2022
Oxidative stress and mitochondrial dysfunction are among the mechanisms expected to explain the pathogenesis of Huntington's disease. Erythropoietin (EPO) and the Bacillus Calmette-Guérin (BCG) vaccine have neuroprotective effects against ...
Mahmoud A. Senousy   +3 more
semanticscholar   +1 more source

Neuroprotective Effect of Boswellia serrata against 3-NP Induced Experimental Huntington’s Disease

Current Bioactive Compounds
Objectives: The study aimed to assess the neuroprotective effect of Boswellia serrata against 3-NP-induced experimental Huntington’s disease. Background: Previous studies have shown Boswellia to have sedative, analgesic, and anti-tumour effects. Boswellia serrata yields four pentacyclic triterpene acids and boswellic acid, a bioactive substance that
Vinay Kumar   +8 more
openaire   +1 more source

Dapagliflozin improves behavioral dysfunction of Huntington's disease in rats via inhibiting apoptosis-related glycolysis.

Life Science, 2020
AIMS Huntington's disease is a rare neurodegenerative disorder which is associated with defected glucose metabolism with consequent behavioral disturbance including memory and locomotion.
Ayman E El-Sahar   +3 more
semanticscholar   +1 more source

Neuroprotective effect of standardized extracts of threeLactuca sativaLinn. varieties against 3-NP induced Huntington’s disease like symptoms in rats

Nutritional Neuroscience, 2020
The study was aimed to evaluate the efficacy of three commonly consumed Lactuca sativa (LS) Linn. varieties viz., Grand rapid, Lollo rosso and Iceberg (Asteraceae) against 3-NP induced HD like symptoms in rats.Ethanol extracts of leaves of three LS varieties were prepared, and standardized on the basis of quercetin content using HPLC.
Jai, Malik   +3 more
openaire   +2 more sources

Antioxidant and antiapoptotic actions of selegiline protect against 3-NP-induced neurotoxicity in rats.

Naunyn-Schmiedeberg's archives of pharmacology, 2018
The present study was designed to investigate the neuroprotective effect of selegiline on 3-nitropropionic acid (3-NP)-induced neurotoxicity. Selegiline was intraperitoneally injected at doses 2.5, 5, and 10 mg/kg, 3 days prior to and continued daily, 30 min before 3-NP administration. 3-NP (20 mg/kg, i.p.) was administered for four consecutive days. 3-
Sara A, Wahdan   +2 more
openaire   +1 more source

Cr(OH)3-NPs-CNC hybrid nanocomposite: a sorbent for adsorptive removal of methylene blue and malachite green from solutions

Environmental Science and Pollution Research, 2017
In this article, Cr(OH)3 nanoparticle-modified cellulose nanocrystal (CNC) as a novel hybrid nanocomposite (Cr(OH)3-NPs-CNC) was prepared by a simple procedure and used as a sorbent for adsorptive removal of methylene blue (MB) and malachite green (MG) from aqueous solution.
Farzin Nekouei   +4 more
openaire   +3 more sources

Synthesis and characterization of metal nanoparticles templated chitosan-SiO2 catalyst for the reduction of nitrophenols and dyes.

Carbohydrate Polymers, 2018
Different metal nanoparticles (MNPs) templated on chitosan-silica (CH-SiO2) nanocomposite fiber were prepared via simple and fast method of the metal ions uptake by fiber and their subseqent reduction using strong reducing agent.
F. Ali   +6 more
semanticscholar   +1 more source

Crystal Structure of Double Co(NH3)6 3 + Np(V) Malonates Co(NH3)6(NpO2C3H2O4)2A·H2O (A = OH and NO3)

Radiochemistry, 2004
X-ray diffraction analysis of Co(NH3)6(NpO2C3H2O4)2NO3·H2O (I) and Co(NH3)6(NpO2· C3H2O4)2OH·H2O (II) showed that they consist of [NpO2C3H2O4] n n - infinite anionic chains, [Co(NH3)6]3 + cations, NO3 - (I) and OH- (II) anions, and molecules of crystallization water. The anionic chain
I. A. Charushnikova   +2 more
openaire   +1 more source

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