Results 111 to 120 of about 8,097,373 (363)
What are “good outcomes” for adolescents in public mental health settings?
International Journal of Mental Health Systems, 2018 BackgroundIn line with the evidence-based paradigm, routine outcome monitoring and clinical feedback systems are now being recommended and implemented in youth mental health services.
K. O. Lavik +4 more
semanticscholar +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Negotiating Motherhood: the Difficulties and Challenges of Rural First-Time Mothers in Parung, West Java [PDF]
, 2002 A hermeneutic phenomenological study was carried out to explore the difficulties and challenges of being a first-time mother in a rural area in Indonesia.
Afiyanti, Y. (Yati)
core
EDIS, 2012 This is part of the Food Safety on the Farm series, a collection that reviews the generally recognized principles of GAPs as they relate to produce, primarily at the farm level and with particular focus on fresh Florida crops and practices. This publication focuses on GAPs and GHPs relating specifically to worker health and hygiene. Written by Keith R.
Keith R. Schneider +2 more
openaire +1 more source
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Global Public HealthHIV pandemic continues to affect key populations more than the general population, namely young men who have sex with men (MSM) [UNAIDS. (2023). The path that ends AIDS: UNAIDS global AIDS update 2023. Joint United Nations Programme on HIV/AIDS.
Filipa Correia +5 more
doaj +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Kepuasan Pasien Jaminan Persalinan pada Pelayanan Persalinan oleh Bidan Desa di Kabupaten Pati Tahun 2012 [PDF]
, 2013 Universitas Diponegoro Program Pascasarjana Program Magister Ilmu Kesehatan Masyarakat Konsentrasi Administrasi dan Kebijakan Kesehatan Minat Manajemen Kesehatan Ibu dan Anak 2013 ABSTRAK Siti Ni’amah Kepuasan Pasien Jaminan Persalinan pada ...
Dharminto, Dharminto +2 more
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Barriers and facilitators of bystander intervention in response to racism in Colombia
Global Public HealthRacial discrimination is a pervasive global problem. Bystanders who observe racism can intervene to support the targets of racism, but they often fail to do so due to several context-specific barriers.
Minna Lyons +4 more
doaj +1 more source
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source