Results 131 to 140 of about 4,170,992 (325)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Agile policies for antimicrobial resistance: A contextual approach to sustainable health challenges

open access: yesGlobal Public Health
This paper examines contextual conditions for antimicrobial resistance (AMR) policy implementation in Zimbabwe. As an emerging global sustainability challenge, AMR constitutes risks for human, animal and environmental health as well as the long-term ...
Martin Mickelsson, Emma Oljans
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

[SDG 3]: Istanbul Gelisim University Good Health and Well-Being Report: 2021

open access: yes, 2023
About the Report Istanbul Gelisim University (IGU); carries out studies to contribute to the health and quality of life of its students, academic and administrative staff, as well as society in general, and to create creative educational opportunities and social project designs.
openaire   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Editorial: Evidence-based on health benefits: probiotics, micronutrients, and edible plants

open access: yesFrontiers in Nutrition, 2023
Learn-Han Lee   +6 more
doaj   +1 more source

Research in compulsory drug detention centres in China: Characteristics and ethical considerations

open access: yesGlobal Public Health
More than 500 centres in China hold over 300,000 individuals in what has been described by the United Nations as unethical and ineffective compulsory treatment and rehabilitation centres.
Yazid Barhoush, Joseph J. Amon
doaj   +1 more source

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