The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Agile policies for antimicrobial resistance: A contextual approach to sustainable health challenges
This paper examines contextual conditions for antimicrobial resistance (AMR) policy implementation in Zimbabwe. As an emerging global sustainability challenge, AMR constitutes risks for human, animal and environmental health as well as the long-term ...
Martin Mickelsson, Emma Oljans
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
[SDG 3]: Istanbul Gelisim University Good Health and Well-Being Report: 2021
About the Report Istanbul Gelisim University (IGU); carries out studies to contribute to the health and quality of life of its students, academic and administrative staff, as well as society in general, and to create creative educational opportunities and social project designs.
openaire +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
How Good Are Physicians And Chart Reviews At Capturing Health Resources And Drug Utilisation By Patients? Results Of The Pgrx-3 Prospective Real World Dataset Validation Study [PDF]
Lamiae Grimaldi‐Bensouda +4 more
openalex +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Editorial: Evidence-based on health benefits: probiotics, micronutrients, and edible plants
Learn-Han Lee +6 more
doaj +1 more source
Research in compulsory drug detention centres in China: Characteristics and ethical considerations
More than 500 centres in China hold over 300,000 individuals in what has been described by the United Nations as unethical and ineffective compulsory treatment and rehabilitation centres.
Yazid Barhoush, Joseph J. Amon
doaj +1 more source

