Results 191 to 200 of about 36,543,879 (347)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Australian letter, England, ca. 1860 [picture] /
Title from label on verso.; Inscriptions: "No. 114. The Australian Letter. A Study from Life. Photographed and Published by Frank M. Good, London"--On label on verso.; Condition: Soiled, spotting, stained, scratched.; "A wonderfully composed and lit ...
Good, Frank Mason.
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Successful Global Health Research Partnerships: What Makes Them Work?
American Journal of Tropical Medicine and Hygiene, 2016 Chandy C. John, G. Ayodo, P. Musoke
semanticscholar +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Eastern Mediterranean Health Journal [2025; Vol.31, Issue 3]
Eastern Mediterranean Health Journal is the official health journal published by the Eastern Mediterranean Regional Office of the World Health Organization.
World Health Organization. Regional Office for the Eastern Mediterranean
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Are General Practitioners Good for Endogenous Supply and Health [PDF]
We investigate the impact of area general practitioner (GP) supply on individual health in England. If no allowance is made for the endogeneity of GP supply, the effect is positive but not statistically significant.
Hugh Gravelle +2 more
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International Journal of Cardiology Congenital Heart Disease, 2021 Chethan Ram Kasargod Prabhakar +4 more
doaj +1 more source
Evaluating the normative implications of national and international artificial intelligence policies for Sustainable Development Goal 3: good health and well-being. [PDF]
Health Aff SchMazzi F.
europepmc +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source