Newborn screening and referral for congenital anomalies by lay health workers in Pakistan: a mixed-methods study to evaluate the effectiveness of a co-created educational intervention. [PDF]
Junejo S +6 more
europepmc +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Clinical evaluation of restorations made of ELS extra low shrinkage versus APT advanced polymer technology resin composite: a prospective randomized controlled clinical trial up to 3 years. [PDF]
Özsoy-Kaner A +4 more
europepmc +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Longitudinal association between self-rated health and psychological well-being in a sample of Spanish university graduates. [PDF]
Vasilj M +7 more
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Identifying Mental Health Issues in Indian Immigrants in Canada: A Comparison with Non-Indian Immigrants. [PDF]
Kaur S, Rosenberg M.
europepmc +1 more source
[SDG 3]: Istanbul Gelisim University Good Health and Well-Being Report: 2023
About the Report Istanbul Gelisim University (IGU) works to contribute to the healthy and quality life of its students, academic and administrative staff, as well as the community, and to create creative educational opportunities and social project designs.
openaire +1 more source

