Advancing fall risk prediction in older adults with cognitive frailty: A machine learning approach using 2-year clinical data. [PDF]
Park C, Kim N, Kim M, Won CW, Lee BC.
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
The relationship between social support and physical and mental health in an older male population: Evidence from China Health and Retirement Longitudinal Study (CHARLS). [PDF]
Li Y, Xiang Y.
europepmc +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Evaluation of Three Large Language Models' Response Performances to Inquiries Regarding Post-Abortion Care in the Context of Chinese Language: A Comparative Analysis. [PDF]
Xue D, Liao S.
europepmc +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
UN RCE RISE Youth Corps: McLeod Health Free Health Care for Horry County [PDF]
Piziak, Savannah
core +1 more source
Assessing moral injury in health care workers living in secular societies: Introducing the Health care-Moral Injury Scale (HMIS). [PDF]
Fradley K+6 more
europepmc +1 more source