Results 281 to 290 of about 8,269,734 (342)

Evaluating long-acting reversible contraceptive service quality at Manna Woreda health posts, Southwest Ethiopia: a mixed method study. [PDF]

Contracept Reprod Med
Delelegn W, Tadele L, Abera M, Masrie A, Birhanu B, Asefa Y.   +5 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

A proxy measure of clinical insight in psychosis: an electronic health records-based validation study. [PDF]

BJPsych Open
López-Díaz Á, Lopez-Morinigo JD, Ortiz-García de la Foz V, Marín-Mateo H, Ortíz-Jiménez MD, Huarcaya-Victoria JD, Gutiérrez-Talavera G, González-Blanch C, Crespo-Facorro B, Cuesta MJ, Ayesa-Arriola R.   +10 more
europepmc   +1 more source

The Role of Kamishibai Storytelling Technique in Enhancing Preschool Children’s Understanding and Knowledge of the Adverse Effects of Tobacco: Sustainable Development Goal 3 (SDG) (Good Health and Well-Being)

Noor Afiza Abdul Rani, Nur Azzalia Kamaruzaman, Nur Asniza Ishak, Sulastri Samsudin, Sazaroni Md Rashid, Mohd Fadhli Razali, Balamurugan Tangiisuran   +6 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Relative Risk of All-Cause Mortality Associated With Cannabis Use: A Systematic Review and Meta-Analysis of Cohort Studies. [PDF]

Health Sci Rep
Alimoradi Z, Lin CY, Myran DT, Solmi M, Pakpour AH.   +4 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Effectiveness of a Participatory and Culturally Tailored Learning Program for Coronavirus Prevention in Muslim Older Adults With Hypertension and Diabetes: Quasi-Experimental Study. [PDF]

Asian Pac Isl Nurs J
Moolsart S, Phuangsomjit C.
europepmc   +1 more source

The Impact of Savory (satureja hortensis l.) on Stability of Refined and Cold-Pressed Sunflower Oil: Contributions to SDG 3 - Good Health and Well-Being

Violeta Ognenoska, Gorica Pavlovska, Maša Knez Marevci, Anka Trajkovska Petkoska, Vesna Rafajlovska   +4 more
openalex   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source