Results 81 to 90 of about 8,200,702 (392)
A variety of neural substrates are implicated in the initiation, coordination, and stabilization of voluntary movements underpinned by adaptive contraction and relaxation of agonist and antagonist muscles.
Seitaro Iwama+4 more
doaj
The general health of children and adolescents in Germany. Results of the cross-sectional KiGGS Wave 2 study and trends [PDF]
Data from KiGGS Wave 2 show that 95.7% of parents who participated in the survey rated the overall health of their 3 to 17 year-old children as very good or good.
Christina Poethko-Müller+3 more
doaj +1 more source
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard+7 more
wiley +1 more source
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti+2 more
wiley +1 more source
Sustainable Development Goal #3 Good Health and Well-Being: Maternal and Child Health [PDF]
The United Nations General Assembly has created 17 global goals labeled Sustainable Development Goals (SDGs) to create a more peaceful, prosperous, and sustainable planet.
Beitzel, Mary
core +1 more source
Data Science: A Powerful Catalyst for Cross-Sector Collaborations to Transform the Future of Global Health - Developing a New Interactive Relational Mapping Tool [PDF]
The increasingly complex and rapidly changing global health and socio-economic landscape requires fundamentally new ways of thinking, acting and collaborating to solve growing systems challenges. Cross-sectoral collaborations between governments, businesses, international organizations, private investors, academia and non-profits are essential for ...
arxiv
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr+4 more
wiley +1 more source
Research on organic agriculture in the Netherlands : organisation, methodology and results [PDF]
Chapters: 1. Organic agriculture in the Netherlands; 2. Dutch research on organic agriculture: approaches and characteristics; 3. Dutch knowledge infrastructure for organic agricultur'; 4. Sustainable systems; 5. Good soil: a good start; 6.
Hommes, M., Sukkel, W.
core +1 more source
Decision-Focused Evaluation: Analyzing Performance of Deployed Restless Multi-Arm Bandits [PDF]
Restless multi-arm bandits (RMABs) is a popular decision-theoretic framework that has been used to model real-world sequential decision making problems in public health, wildlife conservation, communication systems, and beyond. Deployed RMAB systems typically operate in two stages: the first predicts the unknown parameters defining the RMAB instance ...
arxiv
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang+9 more
wiley +1 more source