Results 81 to 90 of about 8,200,702 (392)

Scalp electroencephalograms over ipsilateral sensorimotor cortex reflect contraction patterns of unilateral finger muscles

open access: yesNeuroImage, 2020
A variety of neural substrates are implicated in the initiation, coordination, and stabilization of voluntary movements underpinned by adaptive contraction and relaxation of agonist and antagonist muscles.
Seitaro Iwama   +4 more
doaj  

The general health of children and adolescents in Germany. Results of the cross-sectional KiGGS Wave 2 study and trends [PDF]

open access: yesJournal of Health Monitoring, 2018
Data from KiGGS Wave 2 show that 95.7% of parents who participated in the survey rated the overall health of their 3 to 17 year-old children as very good or good.
Christina Poethko-Müller   +3 more
doaj   +1 more source

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

open access: yesFEBS Letters, EarlyView.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard   +7 more
wiley   +1 more source

Cytosolic‐enhanced dark Epac‐based FRET sensors allow for intracellular cAMP detection in live cells via FLIM

open access: yesFEBS Letters, EarlyView.
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti   +2 more
wiley   +1 more source

Sustainable Development Goal #3 Good Health and Well-Being: Maternal and Child Health [PDF]

open access: yes, 2019
The United Nations General Assembly has created 17 global goals labeled Sustainable Development Goals (SDGs) to create a more peaceful, prosperous, and sustainable planet.
Beitzel, Mary
core   +1 more source

Data Science: A Powerful Catalyst for Cross-Sector Collaborations to Transform the Future of Global Health - Developing a New Interactive Relational Mapping Tool [PDF]

open access: yesarXiv, 2017
The increasingly complex and rapidly changing global health and socio-economic landscape requires fundamentally new ways of thinking, acting and collaborating to solve growing systems challenges. Cross-sectoral collaborations between governments, businesses, international organizations, private investors, academia and non-profits are essential for ...
arxiv  

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

open access: yesFEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr   +4 more
wiley   +1 more source

Research on organic agriculture in the Netherlands : organisation, methodology and results [PDF]

open access: yes, 2009
Chapters: 1. Organic agriculture in the Netherlands; 2. Dutch research on organic agriculture: approaches and characteristics; 3. Dutch knowledge infrastructure for organic agricultur'; 4. Sustainable systems; 5. Good soil: a good start; 6.
Hommes, M., Sukkel, W.
core   +1 more source

Decision-Focused Evaluation: Analyzing Performance of Deployed Restless Multi-Arm Bandits [PDF]

open access: yesarXiv, 2023
Restless multi-arm bandits (RMABs) is a popular decision-theoretic framework that has been used to model real-world sequential decision making problems in public health, wildlife conservation, communication systems, and beyond. Deployed RMAB systems typically operate in two stages: the first predicts the unknown parameters defining the RMAB instance ...
arxiv  

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

open access: yesFEBS Letters, EarlyView.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang   +9 more
wiley   +1 more source

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