Results 81 to 90 of about 8,269,734 (342)

A longer time spent at childcare is associated with lower diet quality among children aged 5–6 years, but not those aged 1.5–2 and 3–4 years: Dietary Observation and Nutrient intake for Good health Research in Japanese young children (DONGuRI) study [PDF]

, 2020
Yui Yoshii, Kentaro Murakami, Keiko Asakura, Shizuko Masayasu, Satoshi Sasaki, Yui Yoshii, Kentaro Murakami, Keiko Asakura, Shizuko Masayasu, Satoshi Sasaki   +9 more
openalex   +1 more source

Evaluasi Kinerja Sistem Informasi Manajemen di Balai Besar Kesehatan Paru Masyarakat Surakarta Berdasarkan Aspek Persepsi Pengguna [PDF]

, 2015
Universitas Diponegoro Fakultas Kesehatan Masyarakat Program Magister Ilmu Kesehatan Masyarakat Konsentrasi Sistem Informasi Manajemen Kesehatan 2015 ABSTRAK Novita Yuliani Evaluasi Kinerja Sistem Informasi Manajemen di Balai Besar Kesehatan ...
Sugiharto, Aris, Suhartono, Suhartono, Yuliani, Novita   +2 more
core  

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

High Autophagy in the Naked Mole Rat may Play a Significant Role in Maintaining Good Health

Cellular Physiology and Biochemistry, 2014
Background/Aims: The maximum lifespan of the naked mole rat is over 28.3 years, which exceeds that of any other rodent species, suggesting that age-related changes in its body composition and functionality are either attenuated or delayed in this ...
Shanmin Zhao, Lifang Lin, Guanghan Kan, Chang Xu, Qiu Tang, Chenlin Yu, Wei Sun, Liping Cai, Chen Xu, Shufang Cui   +9 more
semanticscholar   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source

Analyzing One Health governance and implementation challenges in Mexico

Global Public Health
Establishing a robust One Health (OH) governance is essential for ensuring effective coordination and collaboration among human, animal, and environmental health sectors to prevent and address complex health challenges like zoonoses or antimicrobial ...
Jennifer Hegewisch-Taylor, Anahí Dreser, Alondra Coral Aragón-Gama, María Antonieta Moreno-Reynosa, Celso Ramos Garcia, Arne Ruckert, Ronald Labonté   +6 more
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

The role of gender in antimicrobial resistance: Findings from a scoping review

Global Public Health
Antimicrobial resistance (AMR) is a growing global health threat requiring a strong focus on equity. This scoping review aimed to document the evidence to outline recommendations for gender-responsive AMR policies, programmes, and interventions aligned ...
Arne Ruckert, Zlatina Dobreva, Suzanne Garkay Naro, Sarah Paulin, Lindsay A. Wilson, Clare McGall, Rosemary Morgan, Mimi (Meheret) Melles-Brewer, Anna Coates, Giada Tu Thanh, Esmita Charani, Amparo Gordillo-Tobar, Deepshikha Batheja, Susan Rogers Van Katwyk   +13 more
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source