Results 181 to 190 of about 9,649,671 (339)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Open-Label Study Assessing Relative and Absolute Bioavailability of Oral Camizestrant Formulations and Food Effects in Healthy Postmenopausal Women. [PDF]

Clin Transl Sci
Sykes A, Engman H, Taylor N, Brier T, Maudsley R, Kirova B, Mathewson AM, Bragg RA, Gränfors M, Gangl ET, Klinowska T, Li Y, Menakuru SR, Roe C, McDermott J, Lindemann JPO.   +15 more
europepmc   +1 more source

Application of Doehlert experimental design in the optimization of experimental variables for the Pseudozyma sp. (CCMB 306) and Pseudozyma sp. (CCMB 300) cell lysis [PDF]

, 2012
Amanda Reges de Sena, Gildomar Lima Valasques, Ingara Keisle São Paulo Barretto, Sandra Aparecida de Assis   +3 more
openalex   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Phase 1b/2 study of BMS-813160, a CCR2/5 dual antagonist, in combination with chemotherapy or nivolumab in patients with advanced pancreatic or colorectal cancer. [PDF]

J Immunother Cancer
Le DT, Folprecht G, Varghese AM, Gutierrez M, Noel M, Trikalinos NA, Chen E, Dayyani F, Davis SL, Ma WW, BasuMallick A, Garrido-Laguna I, Osawa M, O'Brien S, Novosiadly RD, Xu K, Greenawalt DM, Dutta S, Twyman Saint Victor C, Lenz HJ.   +19 more
europepmc   +1 more source

Ultrasonic fatigue tests on maraging 300 steel: Under solution annealed, after aging heat treatment and under pre-corrosion attack

Julio A. Ruiz Vilchez, Gonzalo M. Domínguez Almaraz, Aymeric E. Domínguez   +2 more
openalex   +1 more source

CALCULATION OF PERFORMANCE OF COAL-PULVERISATION SYSTEMS OF BOILERS TTP-312 IN 300 MW POWER UNITS BY BURNING OF NON-PROJECT FUELS

, 2015
Stepan Josifovich Mysak
openalex   +2 more sources

Mask at 300 m of water-body locations more than 5, 15 and 20 km distant from land

, 2020
Christopher J. Merchant
openalex   +1 more source

Generation of high-energy neutrons with the 300-ps-laser system PALS [PDF]

, 2014
J. Krása, D. Klír, A. Velyhan, E. Krouský, M. Pfeifer, K. Řezáč, J. Cikhardt, K. Turek, J. Ullschmied, K. Jungwirth   +9 more
openalex   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source