Results 141 to 150 of about 3,089,659 (273)

PD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy

Advanced Science, EarlyView.
The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.
Huixin Gao, Lijuan Lu, Xiaoxiao Xiong, Yi Li, Donghui Hu, Duo Zhang, Zhiwei Feng, Cong Liu, Nannan Liu, Xiaoli Li, Jizhou Tan, Ting Liu, Ling Peng, Lu Lu, Huiyi Feng, Yan Zhong, Guisen Tan, Zhicheng Zhang, Liqin Huang, Chao Su, Ying Xue, Shuo Song, Wenxia Fan, Wei Wang, Fan Zou   +24 more
wiley   +1 more source

Editorial 30(1), 2015

Investigación y Postgrado
Moraima Esteves
doaj   +4 more sources

Three alternative promoters govern PGC-1α expression in chicken and are directly repressed by PPARγ. [PDF]

Poult Sci
Huang J, Mu F, Lou M, Gao F, Ning B, Luo H, Yan X, Jing Y, Wang N.   +8 more
europepmc   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

RETRACTED: Exosomes derived from human umbilical cord Wharton's jelly mesenchymal stem cells ameliorate experimental lymphedema

Clinical and Translational Medicine, 2021
Zhao Ting, Yan Zhi‐xin, Tan You‐wen, Yang Fu‐ji, Sun Hui, Mao Fei, Zhu Wei, Xu Wen‐rong, Qian Hui, Yan Yong‐min   +9 more
doaj   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Cover 30(1) 2018

Humaniora, 2018
Humaniora Humaniora
doaj  

Clinical implementation of endolysins targeting gram-positive bacteria points toward a combination strategy with standard-of-care antibiotics: a selective review. [PDF]

Eur J Med Res
Vander Elst N.
europepmc   +1 more source

Electron‐Phonon Interactions Facilitating Large Polaron‐Related Charge‐Carrier Dynamics for Efficient Perovskite Nanocrystal Solar Cells

Advanced Science, EarlyView.
We developed a custom‐synthesized ligand, 2‐thiophenepropenammonium iodide, to exchange the native ligands capped on inorganic perovskite nanocrystals (NCs), and identified that the significantly decreased strength of electron‐phonon interaction benefited the charge‐carrier dynamics in their assembled films.
Wei Guo, Jinfei Dai, Shuaiqi He, Lin Yang, Yanni He, Jianing Duan, Hanlin Cen, Xiaolong Yang, Fang Yuan, Jingrui Li, Zhaoxin Wu, Liberato Manna, Jun Xi   +12 more
wiley   +1 more source

Deep Learning-Based 3D Reconstruction for Defect Detection in Shipbuilding Sub-Assemblies. [PDF]

Sensors (Basel)
Arcano-Bea P, García-Fischer A, Gómez-González PP, Zayas-Gato F, Calvo-Rolle JL, Quintián H.   +5 more
europepmc   +1 more source