Results 11 to 20 of about 2,903,851 (295)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Exploring the dark accelerator HESS J1745-303 with Fermi Large Area Telescope

, 2011
We present a detailed analysis of the gamma-ray emission from HESS J1745-303 with the data obtained by the Fermi Gamma-ray Space Telescope in the first ~29 months observation.The source can be clearly detected at the level of ~18-sigma and ~6-sigma in 1 ...
A. K. H. Kong, Abdo, Abdo, Abdo, Aharonian, Bamba, Bamba, Bamba, Bamba, C. Y. Hui, Castro, Cheng, Chernyakova, Dogiel, E. M. H. Wu, Hales, Hartman, Inui, J. H. K. Wu, K. S. Cheng, Koyama, Koyama, Koyama, Manchester, Matsumoto, Murakami, Murakami, Nakajima, Nobukawa, Ohnishi, P. H. T. Tam, R. H. H. Huang   +31 more
core   +1 more source

Design to reliability shielded vertical interconnection applied to microwave Chip Scale Packaging [PDF]

, 2000
This paper presents the electrical design, measurement and reliability ests of a shielded vertical interconnection dedicated to microwave solder-mount packages. Electromagnetic simulations show very good results up to 20 GHz.
Adam, T., Cazaux, Jean-Louis, Cogo, B., Drevon, C., Lacoste, J.L., Monfraix, P., Naudy, G., Roux, J.L.   +7 more
core   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Agro-morphological traits and SSR markers reveal genetic variations in germplasm accessions of Indian mustard – An industrially important oilseed crop

Heliyon, 2022
Indian mustard is an economic and highly important industrial oilseed crop. In this study, genetic diversity among 135 Indian mustard germplasm accessions was evaluated using 11 agro-morphological descriptors and 227 SSRs.
Lal Singh, J. Nanjundan, Deepika Sharma, K.H. Singh, Nehanjali Parmar, Rohit Jain, Ajay Kumar Thakur   +6 more
doaj   +1 more source

Long Term X-ray Monitoring Of The TeV Binary LS I +61 303 with RXTE

, 2008
We report on the results of a long term X-ray monitoring campaign of the galactic binary LS I +61 303 performed by the Rossi X-ray Timing Explorer. This dataset consists of 1 ks pointings taken every other day between 2007 August 28 until 2008 February 2.
A. Falcone, A. Smith, Acciari, Barthelmy, Belloni, Blackburn, Bosch-Ramon, D. Pandel, Dhawan, Dubus, Dubus, G. Maier, Goldoni, Gregory, Harrison, J. Holder, Jahoda, Leahy, M. Stroh, Maraschi, P. Kaaret, Paredes, Paredes, Paredes, Sguera, Taylor, Zdziarski   +26 more
core   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

On a selection principle for multivalued semiclassical flows [PDF]

, 2014
We study the semiclassical behaviour of solutions of a Schr ̈odinger equation with a scalar po- tential displaying a conical singularity. When a pure state interacts strongly with the singularity of the flow, there are several possible classical ...
Athanassoulis, Agissilaos, Katsaounis, Theodoros, Kyza, Irene   +2 more
core  

Radio QPO in the ${\gamma}$-ray-loud X-ray binary LS I +61${^\circ}$303

, 2017
LS I +61${^\circ}$303 is a $\gamma$-ray emitting X-ray binary with periodic radio outbursts with time scales of one month. Previous observations have revealed microflares superimposed on these large outbursts with periods ranging from a few minutes to ...
Angelakis, Emmanouil, Fuhrmann, Lars, Jaron, Frederic, Li, Guang-Xing, Massi, Maria, Myserlis, Ioannis, Sharma, Richa, Shi, Xun   +7 more
core   +1 more source