Results 221 to 230 of about 81,473 (273)

Abstract 3053: Comparative validation of neuroblastoma cell lines using flow cytometry and CyToF

Cancer Research, 2023
Introduction The validation of patient derived cell lines and other biologics has gained importance due to more frequent laboratory collaborations.
David H. Mulama, Roman J. Riveria, Kimberly Q. McKinney, Divya Gandra, Kaitlyn H. Smith, Nicholas E. Tastet, G. Sholler   +6 more
semanticscholar   +1 more source

ENGOT-en11/GOG-3053/KEYNOTE-B21: Phase 3 study of pembrolizumab or placebo in combination with adjuvant chemotherapy with/without radiotherapy in patients with newly diagnosed high-risk endometrial cancer.

Journal of Clinical Oncology, 2021
TPS5608 Background: Pembrolizumab, a selective humanized anti–PD-1 monoclonal antibody, has demonstrated activity in patients with previously treated mismatch repair (MMR) deficient (dMMR; 57.1% ORR as monotherapy and 63.6% ORR as combination therapy ...
T. Gorp, M. Mirza, A. Lortholary, D. Cibula, A. Walther, A. Savarese, M. Barretina-Ginesta, F. Ortaç, C. Papadimitriou, L. Bodnar, Chyong-Huey Lai, J. Korach, C. Marth, K. Hasegawa, Xing Xie, E. Barber, R. Coleman, S. Keefe, R. Orlowski, B. Slomovitz   +19 more
semanticscholar   +1 more source

Abstract 3053: Using individual or a consortium of bacteria for immuno-oncology research

Cancer Research, 2022
Preclinical and clinical studies have shed light on the beneficial role of bacteria for cancer therapy. Indeed, these studies have demonstrated that these microorganisms have beneficial properties that allow them to selectively colonize tumor and that ...
Sylvie Maubant, Marie Leblanc, Elisabeth Bertrand, Audrey Bertaux, Loïc Morgand, M. Ramelet, M. Lux, O. Duchamp, Fabrice Vivani   +8 more
semanticscholar   +1 more source

3053 Efficacy and safety of daridorexant in patients with chronic insomnia disorder and comorbid nocturia

Age and Ageing
Chronic insomnia and nocturia are frequently associated, particularly in older adults impacting sleep quality, daytime functioning and quality of life.
J. Khoo, K. Lederer, S. Schoffner, J. B. Miranda, R. Rowles, A. Olivieri, M. Meinel   +6 more
semanticscholar   +1 more source

Abstract 3053: Knockout of UCP2 suppresses skin carcinogenesis

Cancer Research, 2015
Abstract Mitochondria are important and necessary components of cell organelles. In recent times, mitochondrial metabolism has regained attention due to the growing evidence suggesting that dysfunction of mitochondria could play a major role in cancer. Cancer cells that are actively proliferating have great demand for ATP.
Annapoorna Sreedhar, Chunjing Zhang, Yunfeng Zhao   +2 more
openaire   +1 more source

Abstract 3053: SHP2 inhibition with RMC4630 demonstrates antitumor efficacy and potentiates nanoparticle-paclitaxel response in pancreatic cancer

Cancer Research
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with a grim prognosis. The combination of nab-paclitaxel and gemcitabine (NPT-GEM) remains the standard treatment for advanced and metastatic PDAC, achieving a median survival of
Nicola Grimaldi, Lily Darman, Mitchel Ramos, Margaret Schwarz, N. Awasthi   +4 more
semanticscholar   +1 more source

Statistical Analysis of Femoral Neck Fractures Based on 3053 Cases

Clinical Orthopaedics and Related Research, 1987
Femoral neck fractures in 2289 women and 764 men (total 3053) from the years 1975-1977 in Stockholm County Council were retrospectively analyzed regarding social and demographic classification. Seventy-nine percent of the patients (2418 of 3053) were admitted directly from their homes, more commonly in central city areas (82%) than in rural areas (74%).
S, Holmberg, K G, Thorngren
openaire   +2 more sources

Abstract 3053: An Emerging Role Of The RNA Binding Protein Human Antigen R In Atherosclerotic Vascular Smooth Muscle Cell Heterogeneity

Arteriosclerosis, Thrombosis and Vascular Biology
Objective: Lineage tracing studies have shown that advanced atherosclerosis causes vascular smooth muscle cells (VSMCs) to become macrophage-like (MLCs), which increases inflammation.
Caris A. Wadding-Lee, Taylor Coughlin, Shannon M. Jones, Megan Jay, A. Lusis, Eric Camerer, M. Civelek, Michael Tranter, A. P. Owens   +8 more
semanticscholar   +1 more source

Abstract 3053: PTEN as a double-edged sword regulates EGFRL858R-induced lung cancer progression

Cancer Research
Lung cancer is the major cause of death worldwide. Activation of oncogenes or inhibition of tumor suppressors causes cancer formation. Previous studies have indicated that Pten, as a tumor suppressor, inhibits cancer formation.
J. Hung
semanticscholar   +1 more source

PP14.8 – 3053: Vitamin D levels in children with epilepsy

European Journal of Paediatric Neurology, 2015
Background Children with epilepsy and intellectual disability have an increased risk of being vitamin D deficient. Multiple factors have been suggested to contribute to this, in particular the use of antiepileptic drugs such as sodium valproate. Objective The aim of the study was to assess the vitamin D levels in paediatric patients with epilepsy.
H. Towse, M. Albery, M. McGowan, I. Hadjikoumi, Y. Hacohen   +4 more
openaire   +1 more source