Results 71 to 80 of about 9,962,484 (204)

Sangramientos más frecuentes en los primeros 30 meses de vida de los hemofílicos Most frequent bleeding disorders in hemophiliacs in the first 30 months of life

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2004
La edad pediátrica del hemofílico constituye uno de los períodos más importantes en su vida, pues permite, en cierta medida, predecir la evolución de la enfermedad. En esta edad comienzan los sangramientos y las primeras hemartrosis.
Martha Sagarra Veranes
doaj  

Validating the Enright Forgiveness Inventory in Ecuador

PsyCh Journal
Research on forgiveness is limited in Ecuador. This study validated the Enright Forgiveness Inventory–30 (EFI‐30) among 960 participants in Ecuador, resulting in robust reliability and validity values. Our findings provide avenues for future research and
Francisca Fariña, Xiang Zhao, Mercedes Novo, Gabriela Acurio   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

The Role of Process Parameters in Shaping the Microstructure and Porosity of Metallic Components Manufactured by Additive Technology

Applied Sciences
Laser Powder Bed Fusion (LPBF) technology represents one of the most promising additive manufacturing methods, enabling the production of components with high geometric complexity and a wide range of industrial and biomedical applications. In this study,
Dariusz Sala, Piotr Ledwig, Hubert Pasiowiec, Kamil Cichocki, Magdalena Jasiołek, Marek Libura, Michał Pyzalski   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Dedicated government conservation land purchase funding attracts philanthropy to progress 30 × 30 protection targets in Australia

Conservation Science and Practice
Land acquisition is an important strategy in some countries to grow the size, representation, and connectivity of protected area networks, and to contribute to the 30 × 30 protection target.
James A. Fitzsimons
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source