Results 91 to 100 of about 297,139 (334)
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Total Body Skin Exam and Number Needed to Screen [PDF]
, 2019 Introduction/Background: Skin cancer screening could impact mortality and morbidity in US adults; however, the effectiveness of widespread screening remains unclear.
Bui, Michael +4 more
core +1 more source
On the measurement of B(E2, 0+ -> 2+) using intermediate-energy Coulomb excitation
, 2007 Coulomb excitation is a standard method used to extract quadrupole excitation strengths of even-even nuclei. In typical analyses the reaction is assumed to be one-step, Coulomb only, and is treated within a semi-classical model.
, , Bohr A, F Delaunay, F M Nunes
core +3 more sources
Discrimination of 5′-terminal start codons by translation initiation factor 3 is mediated by ribosomal protein S1 [PDF]
, 1998 The interrelation between ribosomal protein S1 and IF3 in recognition/discrimination of 5′-terminal start codons by 30S ribosomes has been studied using in vitro toeprinting.
Bläsi, Udo +2 more
core +1 more source
Structural Insights into Methyltransferase KsgA Function in 30S Ribosomal Subunit Biogenesis*
Journal of Biological Chemistry, 2012 Background: The RNA methyltransferase KsgA is required for small ribosomal subunit maturation. Results: Cryo-electron microscopy reveals the structure of the near mature ribosomal subunit in complex with KsgA.
D. Boehringer +3 more
semanticscholar +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Supernova Remnants in the AKARI IRC Survey of the Large Magellanic Cloud
, 2008 We present the near- to mid-infared study of supernova remnants (SNRs) using the AKARI IRC Survey of the Large Magellanic Cloud (LMC). The LMC survey observed about a 10 square degree area of the LMC in five bands centered at 3, 7, 11, 15, and 24 \micron
Ita, Yoshifusa +11 more
core +1 more source
Existence of N\'eel order in the S=1 bilinear-biquadratic Heisenberg model via random loops [PDF]
, 2016 We consider the general spin-1 SU(2) invariant Heisenberg model with a two-body interaction. A random loop model is introduced and relations to quantum spin systems is proved.
Lees, Benjamin
core +2 more sources
Nucleic Acids Research, 2012 Furvina®, also denominated G1 (MW 297), is a synthetic nitrovinylfuran [2-bromo-5-(2-bromo-2-nitrovinyl)-furan] antibiotic with a broad antimicrobial spectrum.
A. Fabbretti +6 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source