Results 191 to 200 of about 551,942 (246)

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source

School life in children with inflammatory bowel diseases: from a national survey to a patient-driven awareness initiative. [PDF]

Crohns Colitis 360
Gianolio L, Silvera V, Bianchi A, Penagini F, Previtali E, Leone S, Zuccotti G, Norsa L.   +7 more
europepmc   +1 more source

Band 7, 310 (Sammlung Friedlaender)

BAND 7, 310 (SAMMLUNG FRIEDLAENDER) Band 7, 310 (Sammlung Friedlaender) (Public Domain ...

core  

Encapsulated Leptin‐Producing Cells Facilitate Entrainment of Circadian Rhythms in Rodents and Nonhuman Primates

Advanced Science, EarlyView.
A clinically translatable cell line can be engineered to produce leptin, encapsulated in biomaterial and safely implanted to produce and deliver the metabolic regulating protein within the body. Implantation of these encapsulated cells decreases the time it takes for mice and non‐human primates to adjust to circadian disruptions similar to those ...
Samantha T. Fleury, Xuanyi Lin, Peter D. Rios, Christopher Olker, Eun Joo Song, Alejandra Cobos Perez, Cody Fell, Daisy Lopez, Ira Joshi, Hafsa Nasir, Cecelia Curtis, Danna Muringi, Kaiyuan Wang, José Oberholzer, Fred W. Turek, Isaac B. Hilton, Jonathan Rivnay, Martha Hotz Vitaterna, Omid Veiseh   +18 more
wiley   +1 more source

Prevalence and Risk Factors of Asymptomatic Bacteriuria Among Pregnant Women Attending a Tertiary Care Hospital in Jaipur, India. [PDF]

Cureus
Saini S, Panda J, Sharma SP, Khayyam N, Saini VK.   +4 more
europepmc   +1 more source

Band 2, 310 (Sammlung Friedlaender)

BAND 2, 310 (SAMMLUNG FRIEDLAENDER) Band 2, 310 (Sammlung Friedlaender) (Public Domain ...

core  

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Carbon dots derived from <i>Sanguisorbae Radix</i> mitigate intestinal injury after severe burns: mechanisms involving barrier enhancement and oxidative stress amelioration. [PDF]

Front Mol Biosci
Liu L, Zhao Y, Feng B, Li M, Xu S, Yan X, Wang J, Li D, Shen C.   +8 more
europepmc   +1 more source

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

Advanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang, Zuomeng Wu, Ruocheng Guo, Cancan Wang, Yue Qin, Yixiang Dong, Aoyun Li, Ao Liu, Chongyu Jia, Tianyu Han, Peiwen Song, Lei Chen, Cailiang Shen   +12 more
wiley   +1 more source

Periodic extreme rainfall in a warmer climate due to stronger convectively coupled waves. [PDF]

Sci Adv
Quan H, Zhang Y, Dagan G, Fueglistaler S.   +3 more
europepmc   +1 more source