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Rational Design of Inner Ear Drug Delivery Systems
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu+5 more
wiley +1 more source
Role of Composition and Temperature in Shaping the Structural and Optical Properties of Iodide-Based Hybrid Perovskite Thin Films Produced by PVco-D Technique. [PDF]
Marjanowska A+4 more
europepmc +1 more source
This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang+13 more
wiley +1 more source
Tracer diffusion of Au and Cu in a series of near Σ=5 (310)[001] symmetrical Cu tilt grain boundaries [PDF]
E. Budke+4 more
openalex +1 more source
Diffracted X-ray blinking reveals signature crystal polymorph dynamics in 1,2,3,5-Tetrabromobenzene. [PDF]
McGehee K+8 more
europepmc +1 more source
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi+20 more
wiley +1 more source