Results 291 to 300 of about 2,942,407 (405)

Uncovering Interfacial Oxygen‐Bridged Binuclear Metal Centers of Heterogenized Molecular Catalyst for Water Electrolysis

open access: yesAdvanced Science, EarlyView.
In situ Raman monitoring of an electrochemically induced interfacial oxygen‐bridged Cu(III)‐O‐Au binuclear center in heterogenized molecular catalysts, could combine surface hydroxyl groups to form the important intermediate of Cu(III)‐OOH‐Au, which then turns into Cu(III)‐OO‐Au to release O2.
Zhou Yu   +9 more
wiley   +1 more source

Microglial MS4A4A Protects against Epileptic Seizures in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This study has unveiled significant new insights into the role of MS4A4A in Alzheimer's disease‐related epilepsy, highlighting its impact on microglial phagocytosis, mitochondrial metabolism, and cytoskeleton, and demonstrating its therapeutic potential in epilepsy management.
Meng Jiang   +10 more
wiley   +1 more source

The question of strains in AA amyloidosis. [PDF]

open access: yesSci Rep
Westermark GT   +5 more
europepmc   +1 more source

Orbital Coupling and Spin Textures of Fe/Pd Thin Films Grown on Si Substrate with High Magnetic Fields

open access: yesAdvanced Science, EarlyView.
High magnetic fields (HMFs) regulate orbital coupling and spin polarization in Fe/Pd thin films, promoting crystallization and ordered spin textures. HMF‐assisted growth transitions Fe from amorphous to dense 2D structures, enhancing saturation magnetization and domain uniformity. This strategy advances the design of high‐performance spintronic devices
Xuefeng Wu   +6 more
wiley   +1 more source

Enhanced Catalytic Cycle of Glucose Oxidation and Reactive Species with ROS and RHS Generation Mediated by Galvanic Engineering of Dual Atomic Sites on Covalent Organic Frameworks Demonstrating Synergistic Bimetal Tumor Treatment

open access: yesAdvanced Science, EarlyView.
A galvanic replacement is used to control dual atomic metals (Au and Ir) on a covalent organic framework (COF) nanoparticle and then coated with hyaluronic acid (HA). Under a specific bimetallic ratio (COF/Aux/Ir1‐x), the optimization can be achieved for the conversion of intracellular nutrients into reactive species (HOCl and O2• ─) and effectively ...
Wei‐Chung Pan   +9 more
wiley   +1 more source

QSOX2‐Mediated Disulfide Bond Modification Enhances Tumor Stemness and Chemoresistance by Activating TSC2/mTOR/c‐Myc Feedback Loop in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
High QSOX2 enhances stemness, drug resistance, and metastasis of ESCC cells. QSOX2‐mediated disulfide bond modification activates mTOR/c‐Myc signaling. CAFs‐secreted IGF‐1 drives mTOR/c‐Myc/QSOX2 positive feedback loop. Combining Ebselen, rapamycin, and cisplatin induces tumor dormancy in mice.
Wo‐Ming Chen   +12 more
wiley   +1 more source

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