Results 101 to 110 of about 252,838 (244)

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

Advanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt, Shahrzad Rokhsary, Linus Hübner, Lea Miebach, Sander Bekeschus   +4 more
wiley   +1 more source

Untersuchung von Anti‐Glykan‐Antikörpern und Erforschung ihres medizinischen Potenzials mithilfe synthetischer Glykane

Angewandte Chemie, EarlyView.
Anti‐Glykan‐Antikörper spielen sowohl bei Gesundheit als auch bei Krankheit eine wesentliche Rolle. Der Zugang zu neuartigen Glykanstrukturen ermöglicht Fortschritte bei der Antikörpercharakterisierung für die Entdeckung von Biomarkern, die Antikörperentwicklung und das Impfstoffdesign.
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Von In‐Silico bis In‐Cerebro – Entwicklung des Orexinrezeptor Antagonisten „Photorexant“ zur Photomodulation In Vitro und im Gehirn der Maus

Angewandte Chemie, EarlyView.
Durch einen strukturbasierten Designansatz wurden photoschaltbare Derivate des von der FDA zugelassenen Arzneistoffes Suvorexant entwickelt, gedockt, synthetisiert und pharmakologisch an den Orexin‐1‐ und 2‐Rezeptoren (OX1R und OX2R) charakterisiert.
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, EarlyView.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, EarlyView.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

Experimental Characterization of Thermal, Acoustic, Magnetic, and Electrical Properties of Additive Manufactured Composites Reinforced With Ceramic Powders for Robotic Arms

Journal of Applied Polymer Science, Volume 142, Issue 16, April 20, 2025.
ABSTRACT An extensive experimental analysis was conducted to assess the thermal, acoustic, magnetic, and electrical properties of composite materials reinforced with varying ratios of silicon carbide (SiC) and alumina (Al₂O₃) powders, with a focus on enhancing the functionality of robotic arms.
Merdan Özkahraman, Mevlüt Yunus Kayacan, Ali Nadi Kaplan   +2 more
wiley   +1 more source

Severe neonatal complications and long-term health-related quality of life in very preterm and/or very low birth weight survivors: evidence from the Dutch Project on preterm and small for gestational age cohort. [PDF]

Qual Life Res
Bolbocean C, van Dommelen P, van der Pal S.   +2 more
europepmc   +1 more source

In Situ Generation of a Robust Gel Polymer Electrolyte From a Poly(Ethylene Carbonate)‐Hydrogenated Nitrile Butadiene Rubber Containing Thermoplastic Vulcanizate Electrolyte

Journal of Applied Polymer Science, EarlyView.
A gel polymer electrolyte thermoplastic vulcanizate (GPE–TPV) was prepared by blending HNBR and PEC by melt extrusion then thermally decomposing PEC to yield liquid EC. EC is absorbed into the crosslinked HNBR, yielding an electrolyte that is mechanically and electrochemically stable enough to permit cycling in a LiFePO4–Li half‐cell.
Rozita Sadeghzadeh, Gabrielle Foran, Julien Mimeault, Caroline St‐Antoine, Arnaud Prébé, Mickael Dollé   +5 more
wiley   +1 more source

Validation of a Mucosal IgA Assay for SARS-CoV-2. [PDF]

Microorganisms
Zhu M, Massuda E, Cloney-Clark S, Patel U, Parekh A, Gorinson A, Klindworth A, Ahmadi A, Cai MR, Bennett C, Kalkeri R, Plested JS.   +11 more
europepmc   +1 more source

P-314

Epidemiology, 2012
Tom Luben, Jason Sacks, Allen Davis
openaire   +2 more sources