Results 71 to 80 of about 271,035 (240)

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

open access: yesAdvanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang   +12 more
wiley   +1 more source

Impact of recycled glass and carbon geogrids on crack propagation resistance in asphalt concrete

open access: yesRoads and Bridges
The paper analyses the impact of recycled geogrid fibres on the mechanical and physical properties of asphalt concrete. Survey results indicate that the knowledge in this area is very limited.
Grzegorz Mazurek   +5 more
doaj   +1 more source

Quaternary Lidocaine Derivatives: Past, Present, and Future

open access: yesDrug Design, Development and Therapy, 2021
Qi Wang,1 Yujun Zhang,1 Jin Liu,1,2 Wensheng Zhang1,2 1Department of Anesthesiology, Laboratory of Anesthesia and Critical Care Medicine, Translational Neuroscience Centre, West China Hospital, Sichuan University, Chengdu, People’s Republic of ...
Wang Q, Zhang Y, Liu J, Zhang W
doaj  

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

open access: yesAdvanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu   +8 more
wiley   +1 more source

Verification of Numerical Models of Steel Bar Coverings Using Experimental Tests—Preliminary Study

open access: yesMetals
In the design of metal bar coverings, the key problem is to correctly determine the numerical model of the analyzed structure. The description of numerical models may differ from the actual, real behavior of the structure.
Paweł Zabojszcza   +2 more
doaj   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

open access: yesAdvanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung   +7 more
wiley   +1 more source

Investigations of Flow Boiling in Mini-Channels: Heat Transfer Calculations with Temperature Uncertainty Analyses

open access: yesEnergies
The article aims to explore boiling heat transfer in mini-channels with a rectangular cross-section using various fluids (HFE-649, HFE-7000, HFE-7100, and HFE-7200).
Magdalena Piasecka   +4 more
doaj   +1 more source

Identification of Sake Extract as a New Anti-melanogenic Ingredient by and Clinical Trials

open access: yesNatural Product Communications, 2013
Overproduction of melanin is the cause of skin hyperpigmentation, which is related to several skin diseases and cosmetic concerns. Sake is a Japanese alcoholic beverage produced from rice and water by fermentation, but is little known for its effect on ...
Jeong-Ah Hwang   +7 more
doaj   +1 more source

Multispectral UV Imaging on Capacitive CMOS Arrays Enabled by Solution‐Processed Metal‐Oxide Nanoparticles

open access: yesAdvanced Science, EarlyView.
Ultraviolet (UV) imagers are important for a variety of applications but often require dedicated semiconductor process flows. Here, a versatile capacitive CMOS platform is transformed into a visible‐blind, multispectral UV imager through post‐CMOS functionalization with solution‐processed metal‐oxide nanoparticles. The UV‐induced photodielectric effect
Suman Kundu   +5 more
wiley   +1 more source

Primary Prevention of Atherosclerotic Cardiovascular Disease Fails in Young Individuals According to Recent Data in The Netherlands

open access: yesHearts
Background: Atherosclerotic cardiovascular disease (ASCVD) is one of the most important causes of morbidity worldwide. Registries show an impressive decline in prevalent ASCVD morbidity over the last years.
Juliette J. Crooijmans   +7 more
doaj   +1 more source

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