Results 111 to 120 of about 2,510,486 (323)

The European Union’s Myanmar Policy: Focused or Directionless?

Journal of Current Southeast Asian Affairs, 2015
What is the European Union (EU) trying to achieve in Myanmar? Is the EU speaking with one voice and acting collectively (and does it really matter)? Were the sanctions lifted too early?
Jörn Dosch, Jatswan S. Sidhu
doaj  

DeepMarks: A Digital Fingerprinting Framework for Deep Neural Networks [PDF]

, 2018
This paper proposes DeepMarks, a novel end-to-end framework for systematic fingerprinting in the context of Deep Learning (DL). Remarkable progress has been made in the area of deep learning.
Chen, Huili, Koushanfar, Farinaz, Rohani, Bita Darvish   +2 more
core   +1 more source

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Betwixt Droughts and Floods: Flood Management Politics in Thailand

Journal of Current Southeast Asian Affairs, 2015
Attempting to create greater understanding of the political dynamics that influence domestic disaster relief and management (DRM) in Thailand, this article takes a closer look at these dynamics by outlining the main actors involved in flood-related DRM ...
Naila Maier-Knapp
doaj  

322. Risk Factors for COVID-19 Disease Severity Using Electronic-Health Records in a Real-World Cohort in the United States [PDF]

, 2021
Shemra Rizzo, Ryan W. Gan, Devika Chawla, Kelly A. Zalocusky, Xin Chen, Yifeng Chia   +5 more
openalex   +1 more source

Senescent Synovial Intimal Fibroblasts Aggravate Osteoarthritis by Regulating Macrophage Polarization and Chondrocyte Phenotype Through ANGPTL4‐α5β1 Axis

Advanced Science, EarlyView.
Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng, Yunsheng Jiang, Zhiyu Chen, Kaiquan Chen, Na Cao, Yang Huang, Zhengxue Quan, Cheng Chen   +7 more
wiley   +1 more source

Incumbents without a Campaign Finance Advantage: Competition and Money in Chile’s Congressional Elections Sin una ventaja financiera: Incumbentes y el gasto electoral en las elecciones parlamentarias de Chile

Journal of Politics in Latin America, 2011
Research from various countries has shown that incumbents in legislative elections raise and spend more money when they face a tougher contest. A statistical analysis of Chilean candidates’ campaign finance disclosures shows the opposite: an inverse ...
Joel W. Johnson
doaj  

Closure to “Discussion of ‘Speed Effects in Forging Lubrication’” (1971, ASME J. Lubr. Technol., 93, pp. 322–323) [PDF]

, 1971
P. W. Wallace, J. A. Schey
openalex   +1 more source

Membralin Assembles a MAN1B1–VCP Complex to Target Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation

Advanced Science, EarlyView.
This study identifies Membralin as an ER‐phagy receptor that recruits MAN1B1 and VCP to form a selective ERLAD complex. By sensing dense N‐glycan clusters on viral fusion glycoproteins, this ubiquitin‐independent pathway directs SARS‐CoV‐2 spike, Ebola GP, influenza HA, and HIV‐1 Env to lysosomal degradation, thereby limiting viral infectivity ...
Jing Zhang, Xiaoran Lu, Sunan Li, Tao Wang, Iqbal Ahmad, Yong‐Hui Zheng   +5 more
wiley   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source