Results 51 to 60 of about 2,466,814 (376)

Hydroxychloroquine Associated with Lower Glomerular Filtration Rate Decline in Lupus Nephritis

Arthritis Care &Research, Accepted Article.
Background Hydroxychloroquine (HCQ) protects kidney function in lupus nephritis (LN) by preventing flares, yet some cohort studies show no significant benefit in kidney function with HCQ. Clarifying these conflicting findings by showing early and long‐term benefits of HCQ on kidney function preservation is critical. Therefore, we analyzed data from our
Shivani Garg, Brad Rovin, Brad C. Astor, Tripti Singh, Fauzia Hollnagel, Megan Kuik, Lexie Kolton, Callie Saric, S. Sam Lim, Christie M. Bartels   +9 more
wiley   +1 more source

miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy

Genes & Development, 2017
In this study, Rodriguez-Barrueco et al. analyzed ∼3000 primary tumors and show that miR-424(322)/503 is commonly lost in a subset of aggressive breast cancers; they then describe the genetic aberrations that inactivate its expression.
R. Rodríguez-Barrueco, Erin A Nekritz, F. Bertucci, Jiyang Yu, Felix Sanchez-Garcia, Tizita Z. Zeleke, A. Gorbatenko, D. Birnbaum, E. Ezhkova, C. Cordon-Cardo, P. Finetti, David Llobet-Navás, Jose M. Silva   +12 more
semanticscholar   +1 more source

Tomographic reflection modelling of quasi-periodic oscillations in the black hole binary H 1743-322 [PDF]

, 2016
Accreting stellar mass black holes (BHs) routinely exhibit Type-C quasi-periodic oscillations (QPOs). These are often interpreted as Lense–Thirring precession of the inner accretion flow, a relativistic effect whereby the spin of the BH distorts the ...
A. Ingram, M. Klis, M. Middleton, D. Altamirano, P. Uttley   +4 more
semanticscholar   +1 more source

"Aegeritella superficialis" Bal. et Wis. and A. "tuberculata" Bal. et Wis. ("Deuteromycetes"), epizoic fungi on two "Formica (Hymenoptera: Formicidae)" species in the Iberian Peninsula [PDF]

, 1987
Aegeritella superficialis Bał. et Wił . i A. tuberculata Bał. et Wis. (Deuteromycetes ), fongs epizoics de dues espècies de Formica (Hymenoptera: Formicidae) de la penísula Ibèrica. Aegeritella superficialis Bał. et Wił.
Espadaler, Xavier, Wisniewski, Jerzy
core  

How integrative modelling can break down disciplinary silos [PDF]

This paper has been published in a peer-reviewed journal as: Kragt, M.E., Robson, B.J. & Macleod, C.J.A. (2013) Modellers’ roles in structuring integrative research projects. Environmental Modelling & Software, 39(1): 322-330. DOI: 10.1016/j.envsoft.2012.
Kragt, Marit Ellen, Macleod, Christopher J.A., Robson, Barbara J.   +2 more
core   +2 more sources

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Myanmar’s China Policy since 2011: Determinants and Directions

Journal of Current Southeast Asian Affairs, 2015
This paper argues that a key factor in Myanmar’s new approach towards China since 2011 has been the Myanmar government’s foreign policy goal to reintegrate itself into the international community. The success of this approach is dependent on Myanmarâ€
Maung Aung Myoe
doaj  

miR‐322‐5p targets IGF‐1 and is suppressed in the heart of rats with pulmonary hypertension

FEBS Open Bio, 2018
Pulmonary arterial hypertension (PAH) is characterised by remodelling of the pulmonary vasculature leading to right ventricular hypertrophy. Here, we show that miR‐322‐5p (the rodent orthologue of miR‐424‐5p) expression is decreased in the right ...
Martin Connolly, B. Garfield, A. Crosby, N. Morrell, S. Wort, P. Kemp   +5 more
semanticscholar   +1 more source

Atomic Size Misfit for Electrocatalytic Small Molecule Activation

Advanced Functional Materials, EarlyView.
This review explores the application and mechanisms of atomic size misfit in catalysis for small molecule activation, focusing on how structural defects and electronic properties can effectively lower the energy barriers of chemical bonds in molecules like H2O, CO2, and N2.
Ping Hong, Changfan Xu, Huaping Zhao, Yong Lei   +3 more
wiley   +1 more source

Too Undisciplined to Legislate? Party Unity and Policy-making in Brazil Demasiado indisciplinados para gobernar? Unidad partidaria y elaboración de políticas en Brasil

Journal of Politics in Latin America, 2012
Discipline and cohesiveness of political parties are essential for legislatures to engage in policy-making. Parties in Brazil have historically been considered ideologically weak and uninvolved in policy issues of national importance.
Sylvia Gaylord
doaj