Results 81 to 90 of about 2,504,458 (294)
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Introduction: New Forms of Voter Mobilization in Southeast Asia
Journal of Current Southeast Asian Affairs, 2010 Southeast Asia in the twenty-first century is no longer what it used to be, at least not at its ASEAN core. By the 1990s, competitive elections had (re)emerged as the primary mechanism for the assumption of state office in the Philippines and Thailand ...
Eva-Lotta E. Hedman, Andreas Ufen
doaj
Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions
Advanced Science, EarlyView.This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang +4 more
wiley +1 more source
Journal of Current Southeast Asian Affairs, 2010 Book Review of the edited issue: Clarke, Matthew, Ismet Fanany, and Sue Kenny (eds.) (2010), Post-Disaster Reconstruction: Lessons from Aceh, London/ Washington DC: Earthscan ISBN 978-1-84407-879-0, 266 ...
Antje Missbach
doaj
Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source
Journal of Politics in Latin America, 2009 Government and organized criminal groups co-exist in uneasy equilibrium. Criminal groups adjust their behavior as a function of their own goals and resources in relation to inter-group cooperation and conflict, dynamic markets, and public policies ...
Matthew M. Taylor, John Bailey
doaj
International Journal of Polymer Science, 2016 The purpose of this study was to enhance the scratch resistance of polycarbonate copolymer by using 3,3′-dibenzoyl-4,4′-dihydroxybiphenyl (DBHP) monomer, containing benzoyl moieties on the ortho positions.
Hohyoun Jang +8 more
doaj +1 more source
Advanced Science, EarlyView.A mitochondria‐targeted copper depletion nanoplatform (CYN‐CDA@Alb) was developed to selectively disrupt tumor mitochondria copper, which then reprogrammed the tumor immune microenvironment by depressing PD‐L1 and CD47 expression simultaneously. By doing this, CYN‐CDA@Alb reversed radiotherapy‐induced immune tolerance, showing the potential usage of ...
Zaigang Zhou +10 more
wiley +1 more source
The European Union’s Myanmar Policy: Focused or Directionless?
Journal of Current Southeast Asian Affairs, 2015 What is the European Union (EU) trying to achieve in Myanmar? Is the EU speaking with one voice and acting collectively (and does it really matter)? Were the sanctions lifted too early?
Jörn Dosch, Jatswan S. Sidhu
doaj
Bio‐templated Piezoresistive Yarn for High Sensitivity Movement Monitoring Textiles
Advanced Science, EarlyView.This study developed a conductive coating by biotemplating silver nanoparticles (AgNPs) onto a Potato virus A (PV) particle network, cross‐linked on co‐polyamide‐starch (CoPA‐SS) coils. The combination of CoPA‐SS's shape memory and PV‐AgNP's piezoresistivity achieved high strain sensitivity and minimal hysteresis.
Swarnalok De +10 more
wiley +1 more source