Results 11 to 20 of about 265,231 (345)
As availability of precision therapies expands, a well-validated circulating cell-free DNA (cfDNA)-based comprehensive genomic profiling assay has the potential to provide considerable value as a complement to tissue-based testing to ensure potentially ...
R. Woodhouse+18 more
semanticscholar +1 more source
chi-miR-324-3p Regulates Goat Granulosa Cell Proliferation by Targeting DENND1A
Granulosa cell (GC) proliferation provides essential conditions for ovulation in animals. A previous study showed that DENND1A plays a significant role in polycystic ovary syndrome. However, the modulation of DENND1A in GCs remains unclear.
Yufang Liu+8 more
semanticscholar +1 more source
MicroRNA-324-5p–CUEDC2 Axis Mediates Gain-of-Function Mutant p53-Driven Cancer Stemness
Regulation of cancer stemness has recently emerged as a new gain-of-function (GOF) property of mutant p53. In this study, we identify miR-324-5p as a critical epigenetic regulator of cancer stemness and demonstrate its role in mediating GOF-mutant p53 ...
Dishari Ghatak+4 more
semanticscholar +1 more source
Previous studies have demonstrated that long non-coding RNAs (lncRNAs) serve a key role in the development and progression of several types of cancer, including glioma.
Jiale Zhang+6 more
semanticscholar +1 more source
Progressive or chronic renal diseases arise from a process of destructive renal fibrosis. Therefore, the molecular basis of renal fibrosis has attracted increasing attention.
ShuMei Tang+7 more
semanticscholar +1 more source
Increased hippocampal excitability in miR-324-null mice
MicroRNAs are non-coding RNAs that act to downregulate the expression of target genes by translational repression and degradation of messenger RNA molecules.
D. J. Hayman+16 more
semanticscholar +1 more source
Background Patients with hepatitis B virus (HBV) infection are at high risk of hepatocellular carcinoma (HCC). This study aimed to evaluate the expression of microRNA-324-3p (miR-324-3p) in HBV-related HCC and explore the clinical significance of serum ...
Li Zhao, Qian Yang, Jianbo Liu
semanticscholar +1 more source
Background Gastric cancer (GCa) is one of the six major malignancies in the world with low survival rate. Although there are advances in therapeutic approaches, the prognosis of patients with GCa remains not optimistic.
Zhong Zheng+4 more
semanticscholar +1 more source
Comment: 9 pages, uuencoded gzipped postscript. To appear in ``Galaxies in the Young Universe,'' ed. H. Hippelein, Springer Verlag.
Hyron Spinrad, A. Dey, Mark Dickinson
openaire +4 more sources
Background: In this study, we selected several candidate miRNAs to study their possible relationships with tuberculosis. Results: The expression of hsa_circ_0003528 was negatively correlated with the expression of miR-224-5p, miR-324-5p, miR-488-5p, miR ...
Zikun Huang+7 more
semanticscholar +1 more source