Results 81 to 90 of about 265,231 (345)

Exome Sequencing Reveals the Genetic Architecture of Non‐syndromic Orofacial Clefts and Identifies BOC as a Novel Causal Gene

open access: yesAdvanced Science, EarlyView.
Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He   +16 more
wiley   +1 more source

Identity-building and Democracy in the Philippines: National Failure and Local Responses in Mindanao

open access: yesJournal of Current Southeast Asian Affairs, 2010
The case of the Philippines provides an interesting example of how post-colonial governments in Southeast Asia are trying to govern multi-ethnic nations.
Hannah Neumann
doaj  

Piezoelectric Biomaterials for Bone Regeneration: Roadmap from Dipole to Osteogenesis

open access: yesAdvanced Science, EarlyView.
Piezoelectric biomaterials convert mechanical forces into electrical signals, offering novel strategies to restore and modulate bone microenvironments for tissue engineering. This review examines molecular dipole origins, spatial arrangements, and pseudo‐piezoelectric mechanisms and highlights dipole‐engineering techniques for osteogenesis regulation ...
Xiyao Ni   +7 more
wiley   +1 more source

The Comprehensive Peace Agreement and the Dynamics of Post-Conflict Political Partnership in Sudan Das Umfassende Friedensabkommen im Sudan und die Dynamik politischer Partnerschaft in der Nachkriegsphase

open access: yesAfrica Spectrum, 2009
Most of the researches on peace agreements conclude that powersharing arrangements included in these are mostly to the detriment of longterm democratic transformation.
Einas Ahmed
doaj  

MicroRNA hsa-miR-324-5p Suppresses H5N1 Virus Replication by Targeting the Viral PB1 and Host CUEDC2

open access: yesJournal of Virology, 2018
Highly pathogenic influenza A virus (HPAIV) continues to pose a pandemic threat globally. From 2003 to 2017, H5N1 HPAIV caused 453 human deaths, giving it a high mortality rate (52.74%).
Ashish Kumar   +11 more
semanticscholar   +1 more source

Sugar Functionalized Collagen Material for Local Modulation of Innate Immunity

open access: yesAdvanced Science, EarlyView.
Modulation of the innate immune response at the implant site can significantly influence adaptive immunity. A mannose‐functionalized collagen patch, termed the Local Immunotuning Patch (LIP), has been designed to engage mannose receptors on antigen‐presenting cells while exhibiting antibacterial properties. LIP orchestrates complex immune pathways that
Francesca Taraballi   +10 more
wiley   +1 more source

Alavi, Hamid R., Aira Htenas, Ron Kopicki, Andrew W. Sheperd and Ramon Clarete (eds) (2012), Trusting Trade and the Private Sector for Food Security in Southeast Asia

open access: yesJournal of Current Southeast Asian Affairs, 2014
Book Review of the edited compilation: Alavi, Hamid R., Aira Htenas, Ron Kopicki, Andrew W. Sheperd and Ramon Clarete (eds) (2012), Trusting Trade and the Private Sector for Food Security in Southeast Asia, Washington DC: The World Bank, ISBN: 978-0-8213-
Chung Ming CHIN
doaj  

Upregulation of miR-324-5p Inhibits Proliferation and Invasion of Colorectal Cancer Cells by Targeting ELAVL1

open access: yesOncology Research, 2018
Colorectal cancer (CRC) is a common clinical cancer that remains incurable in most cases. miRNAs are reported to play a part in the development of various tumors.
Chijiang Gu   +3 more
semanticscholar   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

open access: yesAdvanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu   +13 more
wiley   +1 more source

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