Results 201 to 210 of about 318,833 (312)

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu   +6 more
wiley   +1 more source

A Social Entrepreneurship Perspective of De‐Carbonising the Footprint through Recycling Compensation: A Case Study of the NGO Madre Coraje

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This research analyses the carbon footprint of the NGO Madre Coraje, using an integrated methodology that combines the calculator provided by REAS (Red de Economía Alternativa y Solidaria) Navarra and the Life Cycle Assessment (LCA). It quantifies emissions across the three scopes of the Greenhouse Gas Protocol, evaluating both direct and ...
José Fernandez‐Serrano   +2 more
wiley   +1 more source

Concomitant Surgical Ablation Using a Novel Bipolar Radiofrequency Clamp: Outcomes from the TRAC-AF Registry. [PDF]

open access: yesJ Clin Med
Shults C   +17 more
europepmc   +1 more source

In Vitro Metabolism of Δ8‐, Δ9‐, and Δ10‐THC in Human Hepatocytes: Distinct Δ10‐THC Biotransformation and Implications for Drug Testing

open access: yesDrug Testing and Analysis, EarlyView.
Δ8‐THC and Δ9‐THC showed comparable metabolic profiles. In contrast, Δ10‐THC underwent extensive glucuronidation and hydroxylation, with only minor formation of a carboxy metabolite, indicating a markedly different metabolic pathway. These differences may increase the risk of misidentification and misinterpretation in cannabis drug testing.
Robert Kronstrand   +4 more
wiley   +1 more source

Development and Validation of the Body Neutrality Questionnaire

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Body neutrality has emerged as an alternative framework within the positive body image literature. This study developed the Body Neutrality Questionnaire (BNQ), the first validated measure of body neutrality for young adults. Method An initial item pool was developed using expert consultation and focus group review.
Amelia Kimpton   +4 more
wiley   +1 more source

A Thermally Robust Luminescent Antimony Halide for Real‐Time Detection of Volatile Iodine at Elevated Temperatures

open access: yesEcoEnergy, EarlyView.
Zero‐dimensional antimony halides drive efficient iodine capture through electron transfer and display rapid fluorescence quenching at 75°C (348 K), establishing the first luminescent sensor for real‐time I2 detection at elevated temperatures. ABSTRACT Real‐time monitoring of volatile molecular iodine (I2), a hazardous radioactive byproduct of nuclear ...
Ying Jiang   +13 more
wiley   +1 more source

Cinematic rendering of ectopic thyroid tissue. [PDF]

open access: yesQuant Imaging Med Surg
Liang S, Zhang H.
europepmc   +1 more source

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