Results 251 to 260 of about 2,420,843 (334)

Exploration and Characterization of the Antimalarial Activity of Pyrimidine‐2,4‐Diamines for which Resistance is Mediated by the ABCI3 Transporter

open access: yesChemMedChem, EarlyView.
Investigation of the structure‐activity relationship on W482 (1) with a pyrimidine‐2,4‐diamine scaffold culminated in analog 51 with enhanced anti‐plasmodial activity. Forward genetics and phenotypic examination revealed the ABCI3 transporter protein as a putative resistance mechanism.
Mahta Mansouri   +14 more
wiley   +1 more source

Real‐World Effectiveness and Safety of Recombinant Human Follicle‐Stimulating Hormone (rhFSH) in Infertile Women undergoing Assisted Reproductive Technology (ART): A Korean Nationwide Cohort Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Despite widespread rhFSH use in infertile women undergoing ART, real‐world comparative data on its effectiveness and safety across different rhFSH types remain limited. Using the HIRA claims database, we included 10,684 women aged 20–39 with infertility (2016–2021) who used only rhFSH in their first in vitro fertilization–embryo transfer (IVF‐ET ...
Joong Yeup Lee   +12 more
wiley   +1 more source

Bifunctional Molecular Switches in Fused Diarylethene–Rhodamine Systems

open access: yesChemPhotoChem, EarlyView.
Spectroscopic and time‐dependent density‐functional theory studies show that these novel rhodamine‐based diarylethene (DAE) compounds display intense UV absorption, undergo reversible two‐step protonation involving triazole and rhodamine units, and respond selectively to acid, base, and metal ions.
Bassima Hoteit   +5 more
wiley   +1 more source

Frequency of reported abuse, stigma and discrimination during facility-based childbirth among migrant mothers and their suggestions for improvement: a mixed method WHO standards-based multicentre study in Italy. [PDF]

open access: yesBMJ Open
Mariani I   +28 more
europepmc   +1 more source

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