Results 81 to 90 of about 62,336 (316)

Tracking the Evolution of Non‐Small‐Cell Lung Cancer

New England Journal of Medicine, 2017
BACKGROUND Among patients with non‐small‐cell lung cancer (NSCLC), data on intratumor heterogeneity and cancer genome evolution have been limited to small retrospective cohorts.
M. Jamal-Hanjani, G. Wilson, N. Mcgranahan, Nicolai J. Birkbak, T. Watkins, S. Veeriah, S. Shafi, Diana H. Johnson, R. Mitter, R. Rosenthal, M. Salm, S. Horswell, M. Escudero, Nik Matthews, A. Rowan, T. Chambers, D. Moore, S. Turajlic, Hang Xu, S. Lee, M. Forster, T. Ahmad, C. Hiley, C. Abbosh, M. Falzon, E. Borg, T. Marafioti, D. Lawrence, M. Hayward, S. Kolvekar, N. Panagiotopoulos, S. Janes, R. Thakrar, Asia Ahmed, F. Blackhall, Y. Summers, R. Shah, L. Joseph, A. Quinn, P. Crosbie, B. Naidu, G. Middleton, G. Langman, S. Trotter, M. Nicolson, H. Remmen, K. Kerr, M. Chetty, L. Gomersall, D. Fennell, A. Nakas, S. Rathinam, G. Anand, S. Khan, P. Russell, V. Ezhil, Babikir Ismail, Melanie Irvin-sellers, V. Prakash, J. Lester, M. Kornaszewska, R. Attanoos, Haydn Adams, H. Davies, S. Dentro, P. Tanière, Brendan O’Sullivan, H. Lowe, J. Hartley, N. Iles, Harriet Bell, Y. Ngai, J. Shaw, Javier Herrero, Z. Szallasi, R. Schwarz, A. Stewart, S. Quezada, J. Le Quesne, P. Van Loo, C. Dive, A. Hackshaw, C. Swanton   +82 more
semanticscholar   +1 more source

Loss of Golga7 Suppresses Oncogenic Nras‐Driven Leukemogenesis without Detectable Toxicity in Adult Mice

Advanced Science, EarlyView.
NRAS mutations are widespread in hematologic malignancies. Our study shows that GOLGA7 serves as a safe and effective therapeutic target for NRAS‐driven leukemia. Loss of Golga7 in adult mice effectively suppresses NrasG12D‐driven myeloproliferative neoplasm by disrupting its PM localization and impairing subsequent MAPK signaling, without affecting ...
Bo Jiao, Lei Yan, Rui Zhang, Wei Huang, Xinru Wang, Chenxuan Liu, Peihong Wang, Pengfei Xu, Jinzeng Wang, Zhou Fang, Donghe Li, Zhizhou Xia, Jiaoyang Li, Shiyu Ji, Qianqian Zhang, Min Wu, Shengyue Wang, Ping Liu, Ruibao Ren   +18 more
wiley   +1 more source

ASEAN and Strategic Rivalry among the Great Powers in Asia

Journal of Current Southeast Asian Affairs, 2010
This paper looks at ASEAN’s role in the context of the three main bilateral relations among the great powers in Asia: China-US, China-Japan, and China-India.
Fenna Egberink, Frans-Paul van der Putten   +1 more
doaj  

Building consumer trust online

CACM, 1999
M oving some Web consumers along to the purchase click is proving to be difficult, despite the impressive recent growth in online shopping. Consumer online shopping revenues and related corporate profits are still meager, though the industry is ...
D. Hoffman, T. Novak, M. Peralta
semanticscholar   +1 more source

Engineering the Immune Response to Biomaterials

Advanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam, Mehran Bahrami, Einollah Sarikhani, Rumeysa Tutar, Yavuz Nuri Ertas, Faleh Tamimi, Ali Hedayatnia, Clotilde Jugie, Houman Savoji, Asma Talib Qureshi, Muhammad Rizwan, Chima V. Maduka, Nureddin Ashammakhi   +12 more
wiley   +1 more source

Review: Donald Seekins: Burma and Japan since 1940. From ‘Co-Prosperity’ to ‘Quiet Dialogue’ (2008) Buchbesprechung: Donald Seekins: Burma and Japan since 1940. From ‘Co-Prosperity’ to ‘Quiet Dialogue’ (2008)

Journal of Current Southeast Asian Affairs, 2009
Review of the monograph: Donald Seekins: Burma and Japan since 1940. From ‘Co-Prosperity’ to ‘Quiet Dialogue’ Copenhagen: NIAS Press, 2008, ISBN 978 87 7694 017 1, 191 pages Besprechung der Monographie: Donald Seekins: Burma and Japan since 1940.
Hans-Bernd Zöllner
doaj  

Viridicatol from the Deep‐Sea‐Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway

Advanced Science, EarlyView.
Viridicatol (VDC), isolated from the deep‐sea‐derived fungus, enhances osteogenesis in vitro and in vivo by targeting Wnt/SHN3 signaling pathway. It can be delivered via engineered nanovesicles to mitigate bone loss of osteoporosis, fracture repair, and osteogenesis imperfecta.
Chun‐Lan Xie, Shang‐Hui Ye, Yu‐Ting Yue, Bao‐Hong Shi, Jing‐Ping Xu, Lian‐Jie Li, Zheng‐Biao Zou, Matthew B. Greenblatt, Na Li, Xian‐Wen Yang, Ren Xu   +10 more
wiley   +1 more source

Susceptibility of 327 Clinical Isolates to Netilmicin

Journal of International Medical Research, 1978
Netilmicin, a semisynthetic derivative of sisomicin, was tested against 327 isolates of Staphylococcus aureus, Pseudomonas aeruginosa and Gram-negative enteric bacilli. Seventy-two per cent of the isolates were inhibited at a concentration of 0.5 μg netilmicin per ml, and 93% of the isolates were susceptible to 4 μg per ml or less.
Knut Haeger, Asbjørn Digranes, Sigvard Tschudi Madsen, Birgit Østervold, Claus Ola Solberg   +4 more
openaire   +3 more sources

The United States and Myanmar: From Antagonists to Security Partners?

Journal of Current Southeast Asian Affairs, 2015
This article provides an overview both of the considerable makeover that relations between the United States and Myanmar have undergone since Naypyidaw ushered in a programme of wide-ranging reforms, and of the main policy areas in relation to which ...
Jürgen Haacke
doaj  

Cohomologie $L^p$ et pincement [PDF]

Comment. Math. Helv. 83 (2008) 327-357, 2012
A sharp vanishing theorem for the $L^p$ cohomology torsion of Riemannian manifolds with pinched negative curvature is given. It follows that certain negatively curved homogeneous spaces cannot be quasiisometric to better pinched manifolds.
arxiv