Results 131 to 140 of about 384,267 (199)

METTL7A Downregulation Drives SLC1A5‐Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer

Advanced Science, EarlyView.
GC cells enhance glutamine accumulation by upregulating SLC1A5 expression. This upregulation not only boosts GC cell proliferation, but also outcompetes CD8+ T cells for glutamine and suppresses their antitumor immunity. Mechanistically, METTL7A deficiency in GC induces SLC1A5 overexpression via an m6A‐dependent pathway and N‐glycosylation ...
Mingjun Sun, Shuwei Dang, Dazhi Zhou, Lixian Ding, Xun Sun, Wei Suo, Jirui Niu, Qingzhu Yang, Zhicheng Zhang, Yanyan Sun, Jinxing Li, Zhongsheng Chen, Tao Ban, Yingji Wang, Tianzhu Li, Ming Liu, Guodong Li   +16 more
wiley   +1 more source

Effects of the Freezing Diluent Tonicity and Prefreezing Cooling Rates on Post-Thaw Sperm Quality Markers in the Pure-Bred Arabian Stallion. [PDF]

Vet Med Int
Mavalizadeh L, Divar MR, Mogheiseh A, Emami M.   +3 more
europepmc   +1 more source

Self‐Assembly of Organic–Inorganic Copolymers Toward Bio‐Inspired Cementitious Composites

Advanced Science, EarlyView.
Organic–inorganic copolymerization of calcium silicate hydrate and thioctic acid produces a self‐organized nanocomposite inspired by the disordered collagen–mineral architecture of trabecular bone. The resulting material combines a compressive strength above 300 MPa with intrinsic physical reprocessibility, retaining over 80% of its strength and energy
Zonglin Xie, Suning Li, Fuwen Zhong, Gongkun Xiang, Mustapha Jamaa Garba, Yi Tian, Jun Wu, Zhiwu Yu, Qiang Yuan   +8 more
wiley   +1 more source

KPT-330 alleviates osteoarthritis by inhibiting subchondral bone osteoclastogenesis via the NF-κB and MAPK signaling pathways. [PDF]

iScience
Chen W, Liang Y, Liu C, Ling G, Lei S, Huang J, Lin W, Lin C.   +7 more
europepmc   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Harnessing Li‐Ion Binding Energy for Solvation‐Guided Electrolyte Additive Design and Robust Solid Electrolyte Interphase Reinforcement

Advanced Science, EarlyView.
A solvation‐guided design strategy for electrolyte additives is established, identifying Li‐ion binding energy as a crucial determinant for effective interface reinforcement. ABSTRACT The rational design of electrolyte systems is essential for stabilizing the electrode−electrolyte interface to enhance the electrochemical performance of lithium‐ion ...
Jooeun Byun, Ho Yeon Jang, Myung‐Jun Kwak, Chae Rim Lee, Chihyun Hwang, Seoin Back, Hyun‐seung Kim   +6 more
wiley   +1 more source

LncRNA EWSAT1 promotes colorectal cancer progression by regulating the miR-330-5p/CPEB4 axis. [PDF]

Am J Transl Res
Tang CX, Xie DF, Wang XB, Yu HM, Xing FZ, Zhao ZH, Yang T.   +6 more
europepmc   +1 more source

Probing Type‐II Multiferroicity in Monolayer NiBr2

Advanced Science, EarlyView.
Type‐II multiferroicity is demonstrated in monolayer NiBr2. Scanning tunneling microscopy resolves ferroelectric polarization arising from non‐collinear magnetic order, and reciprocal control with electric and magnetic fields confirms intrinsic magnetoelectric coupling.
Aleš Cahlík, Antti Karjasilta, Anshika Mishra, Robert Drost, Mohammad Amini, Javaria Arshad, Büşra Gamze Arslan, Peter Liljeroth   +7 more
wiley   +1 more source

Comment on: effects of emergency department length of stay on inpatient utilization and mortality. [PDF]

Health Econ Rev
Chen CY, Tseng SF, Kao YS, Kuo RN.
europepmc   +1 more source

Metasurface‐Enabled Helical Wavefront Fingerprint Metrology for Quantitative Retrieval of Liquid Optical Constants

Advanced Science, EarlyView.
A metasurface‐enabled helical wavefront fingerprint (MHWF) paradigm is proposed for quantitative and specific retrieval of a liquid medium's refractive index and extinction coefficient. The liquid's complex dielectric response governs the wavefront evolution of the metasurface‐generated focused vortex beam, forming a distinctive three‐dimensional ...
Yuting Zhou, Hongliang Li, Simeng Li, Feiyu Jiao, Yansong Du, Jin Tae Kim, Sang‐Shin Lee, Duk‐Yong Choi, Fei Ding, Xuechao Yu, Xun Guan   +10 more
wiley   +1 more source