Results 281 to 290 of about 2,693,288 (387)

Protective effects of microRNA‐330 on amyloid β‐protein production, oxidative stress, and mitochondrial dysfunction in Alzheimer's disease by targeting VAV1 via the MAPK signaling pathway

Journal of Cellular Biochemistry, 2018
Ying Zhou, Zhouling Wang, Wei Li, Hui-ling Hong, Juan Chen, Yi-Li Tian, Zhao Liu   +6 more
semanticscholar   +1 more source

Enhancing Specificity, Precision, Accessibility, Flexibility, and Safety to Overcome Traditional CRISPR/Cas Editing Challenges and Shape Future Innovations

Advanced Science, EarlyView.
CRISPR/Cas9, while transformative, faces challenges in specificity, precision, delivery, accessibility, flexibility, and safety. This review addresses these limitations by highlighting strategies to reduce off‐target effects, exploring HDR‐based and alternative editing approaches, and evaluating advanced delivery mechanisms.
Muna Alariqi, Mohamed Ramadan, Lu Yu, Fengjiao Hui, Amjad Hussain, Xiaofeng Zhou, Yu Yu, Xianlong Zhang, Shuangxia Jin   +8 more
wiley   +1 more source

Prevalence of Work-Related Musculoskeletal Disorders and Associated Factors Among Doctor of Physical Therapy in Syria: A Cross-Sectional Study. [PDF]

Health Sci Rep
Khadour FA, Khadour YA, Alawdi SA.
europepmc   +1 more source

Surface‐Engineered Cenospheres Encapsulating Phase Change Materials for Functional Cementitious Composites

Advanced Science, EarlyView.
The global energy demand drives the need for advanced energy‐efficient building solutions. While current polymeric‐shell microencapsulated PCMs show promise for thermal energy storage, their use in cementitious materials is challenged by poor shell strength and interfacial bonding. This study develops novel cement‐compatible microencapsulated PCM using
Sahand Rahemipoor, Carsten Kuenzel, Toms Valdemārs Eiduks, Andrei Shishkin, Mohammadreza Izadifar, Neven Ukrainczyk, Eduardus Koenders, Navid Ranjbar   +7 more
wiley   +1 more source

Curcumin Reverses Antibiotic Resistance and Downregulates Shiga Toxin Expression in Enterohemorrhagic <i>E. coli</i>. [PDF]

Diseases
Zermeño-Ruiz M, Cobos-Vargas M, Saucedo-Plascencia MD, Cortés-Zárate R, Hernandez-Hernandez L, Garcia-Cobian TA, Estrada-Garcia T, Castillo-Romero A.   +7 more
europepmc   +1 more source

Author Index for Volume 330

Virology, 2004
openaire   +1 more source

Dual‐Locking the SARS‐CoV‐2 Spike Trimer: An Amphipathic Molecular “Bolt” Stabilizes Conserved Druggable Interfaces for Coronavirus Inhibition

Advanced Science, EarlyView.
A new amphipathic molecule, S416 is discovered, that locks the SARS‐CoV‐2 spike protein in its closed state, blocking viral entry. S416 acts as a molecular bolt, binding six sites: three between adjacent RBDs and three connecting NTDs to RBDs. This dual‐locking mechanism stiffens the spike structure and reduces its flexibility.
Shiliang Li, Fang Ye, Yucheng Zheng, Jie Wang, Haoran Peng, Lili Zhu, Lili Chen, Tao Yu, Huan Ge, Jiaqi He, Binghao Zhang, Jiayun Wu, Zhiyi Zhang, Liangliang Jiang, Geng Chen, Ping Zhao, Ke Lan, Zhenjiang Zhao, Xuhong Qian, Ke Xu, Yang Du, Honglin Li   +21 more
wiley   +1 more source

Kinetic and Isotherm Studies of Organic and Inorganic Anions Adsorption from Water by Quaternized Pentablock Copolymeric Film (PTBr). [PDF]

Polymers (Basel)
Crispi S, Filice S, Scuderi V, Zimbone M, Iannazzo D, Celesti C, Scalese S.   +6 more
europepmc   +1 more source

Expedition 330 summary [PDF]

, 2012
openaire   +1 more source

An Engineered Soluble Single‐Chain TCR Engager for KRAS‐G12V Specific Tumor Immunotherapy

Advanced Science, EarlyView.
This study develops a dimeric T cell receptor engager protein specific for tumor KRAS‐G12V mutation. The engager proteins are capable of mediating the formation of synapse between T cell and tumor cell and demonstrate substantial tumor suppression efficacy.
Keke Ma, Jie Wang, Min Jiang, Juanhua He, Fangyang Li, Dan Lu, Chao Su, Yan Chai, Wenjing Jin, Yu Chen, Catherine W.H. Zhang, Xiaopeng Ma, Hui Tan, George F. Gao, Shuguang Tan   +14 more
wiley   +1 more source