Results 11 to 20 of about 335,877 (277)
Participant 332 Community Conversations Interview
In this interview, Participant 332 shares their experience contracting COVID-19 in January 2020 when there were inadequate testing protocols and many unknowns about the infection.
Johnson-Faniel, Denalerie
core
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Neurons in primary auditory cortex represent sound source location in a cue-invariant manner
The brain's auditory cortex is involved not just in detection of sounds, but also in localizing them. Here, the authors show that neurons in ferret primary auditory cortex (A1) encode the location of sound sources, as opposed to merely reflecting spatial
Katherine C. Wood +2 more
doaj +1 more source
Morphology of the Sella Turcica: A Meta-Analysis Based on the Results of 18,364 Patients
Background: This meta-analysis aimed to present data on the sella turcica (ST) morphology and variations. Furthermore, a detailed morphometric analysis of the ST was conducted.
Tomasz Iskra +11 more
doaj +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Assessing the comparative productivity advantage of bioenergy feedstocks at different latitudes
We evaluate the comparative productivity of maize and sugarcane biofuel feedstocks as a function of latitude. Solar radiation for photosynthesis varies by latitude and contributes to differential productivity of tropical and temperate zones. We calculate
Carlisle Ford Runge +7 more
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source

