Results 11 to 20 of about 216,907 (260)

Morphology of the Sella Turcica: A Meta-Analysis Based on the Results of 18,364 Patients

Brain Sciences, 2023
Background: This meta-analysis aimed to present data on the sella turcica (ST) morphology and variations. Furthermore, a detailed morphometric analysis of the ST was conducted.
Tomasz Iskra, Bartłomiej Stachera, Kamil Możdżeń, Agnieszka Murawska, Patryk Ostrowski, Michał Bonczar, Iwona Gregorczyk-Maga, Jerzy Walocha, Mateusz Koziej, Grzegorz Wysiadecki, Krzysztof Balawender, Andrzej Żytkowski   +11 more
doaj   +1 more source

The Morphology of the Pituitary Gland: A Meta-Analysis with Implications for Diagnostic Imaging

Brain Sciences, 2023
The objective of this meta-analysis was to present transparent data on the morphology of the pituitary gland (PG) using the available data in the literature.
Michał Bonczar, Grzegorz Wysiadecki, Patryk Ostrowski, Mateusz Michalczak, Dawid Plutecki, Jakub Wilk, Weronika Michalik, Jerzy Walocha, Krzysztof Balawender, Tomasz Iskra, Dariusz Lusina, Mateusz Koziej, Maciej Radek, Andrzej Żytkowski   +13 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Neurons in primary auditory cortex represent sound source location in a cue-invariant manner

Nature Communications, 2019
The brain's auditory cortex is involved not just in detection of sounds, but also in localizing them. Here, the authors show that neurons in ferret primary auditory cortex (A1) encode the location of sound sources, as opposed to merely reflecting spatial
Katherine C. Wood, Stephen M. Town, Jennifer K. Bizley   +2 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Assessing the comparative productivity advantage of bioenergy feedstocks at different latitudes

Environmental Research Letters, 2012
We evaluate the comparative productivity of maize and sugarcane biofuel feedstocks as a function of latitude. Solar radiation for photosynthesis varies by latitude and contributes to differential productivity of tropical and temperate zones. We calculate
Carlisle Ford Runge, John J Sheehan, Benjamin Senauer, Jonathan Foley, James Gerber, Justin Andrew Johnson, Stephen Polasky, Carlisle Piehl Runge   +7 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Development of an Analysis Method for 4-Deoxy-l-erythro-5-hexoseulose Uronic Acid by LC/ESI/MS with Selected Ion Monitoring

Natural Product Communications, 2017
This study describes a simple and rapid analytical quantitative method for measuring 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEH) using liquid chromatography-electrospray ionization-mass spectrometry (LC/ESI/MS).
Toshiyuki Shibata, Reona Fujii, Hideo Miyake, Reiji Tanaka, Tetsushi Mori, Mami Takahashi, Toshiyuki Takagi, Hiroyuki Yoshikawa, Kouichi Kuroda, Mitsuyoshi Ueda   +9 more
doaj   +1 more source

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai, Sen Zhang, Haipei Zhang, Yating Zhang, Junhong Guo, Xiaoyan Yang   +5 more
wiley   +1 more source