Results 121 to 130 of about 539 (144)

Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex. [PDF]

Proc Natl Acad Sci U S A, 2001
Baki L, Marambaud P, Efthimiopoulos S, Georgakopoulos A, Wen P, Cui W, Shioi J, Koo E, Ozawa M, Friedrich VL, Robakis NK.   +10 more
europepmc   +1 more source

Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling. [PDF]

EMBO J, 2006
Georgakopoulos A, Litterst C, Ghersi E, Baki L, Xu C, Serban G, Robakis NK.   +6 more
europepmc   +1 more source

Age-related vascular pathology in transgenic mice expressing presenilin 1-associated familial Alzheimer's disease mutations. [PDF]

Am J Pathol, 2010
Gama Sosa MA, Gasperi RD, Rocher AB, Wang AC, Janssen WG, Flores T, Perez GM, Schmeidler J, Dickstein DL, Hof PR, Elder GA.   +10 more
europepmc   +1 more source

Presenilin-1 regulates induction of hypoxia inducible factor-1α: altered activation by a mutation associated with familial Alzheimer's disease. [PDF]

Mol Neurodegener, 2010
De Gasperi R, Sosa MA, Dracheva S, Elder GA.   +3 more
europepmc   +1 more source

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions. [PDF]

EMBO J, 2002
Marambaud P, Shioi J, Serban G, Georgakopoulos A, Sarner S, Nagy V, Baki L, Wen P, Efthimiopoulos S, Shao Z, Wisniewski T, Robakis NK.   +11 more
europepmc   +1 more source

p120 catenin recruits cadherins to gamma-secretase and inhibits production of Abeta peptide. [PDF]

J Biol Chem, 2009
Kouchi Z, Barthet G, Serban G, Georgakopoulos A, Shioi J, Robakis NK.   +5 more
europepmc   +1 more source

Wild-type but not FAD mutant presenilin-1 prevents neuronal degeneration by promoting phosphatidylinositol 3-kinase neuroprotective signaling. [PDF]

J Neurosci, 2008
Baki L, Neve RL, Shao Z, Shioi J, Georgakopoulos A, Robakis NK.   +5 more
europepmc   +1 more source

Presenilin1/γ-secretase protects neurons from glucose deprivation-induced death by regulating miR-212 and PEA15.

FASEB J, 2018
Huang Q, Voloudakis G, Ren Y, Yoon Y, Zhang E, Kajiwara Y, Shao Z, Xuan Z, Lebedev D, Georgakopoulos A, Robakis NK.   +10 more
europepmc   +1 more source

A genetic screen identifies novel polycomb group genes in Drosophila. [PDF]

Genetics, 2007
Gaytán de Ayala Alonso A, Gutiérrez L, Fritsch C, Papp B, Beuchle D, Müller J.   +5 more
europepmc   +1 more source

Acute blast injury reduces brain abeta in two rodent species. [PDF]

Front Neurol, 2012
De Gasperi R, Gama Sosa MA, Kim SH, Steele JW, Shaughness MC, Maudlin-Jeronimo E, Hall AA, Dekosky ST, McCarron RM, Nambiar MP, Gandy S, Ahlers ST, Elder GA.   +12 more
europepmc   +1 more source