Results 71 to 80 of about 293 (84)

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions. [PDF]

EMBO J, 2002
Marambaud P, Shioi J, Serban G, Georgakopoulos A, Sarner S, Nagy V, Baki L, Wen P, Efthimiopoulos S, Shao Z, Wisniewski T, Robakis NK.   +11 more
europepmc   +1 more source

p120 catenin recruits cadherins to gamma-secretase and inhibits production of Abeta peptide. [PDF]

J Biol Chem, 2009
Kouchi Z, Barthet G, Serban G, Georgakopoulos A, Shioi J, Robakis NK.   +5 more
europepmc   +1 more source

Wild-type but not FAD mutant presenilin-1 prevents neuronal degeneration by promoting phosphatidylinositol 3-kinase neuroprotective signaling. [PDF]

J Neurosci, 2008
Baki L, Neve RL, Shao Z, Shioi J, Georgakopoulos A, Robakis NK.   +5 more
europepmc   +1 more source

Presenilin1/γ-secretase protects neurons from glucose deprivation-induced death by regulating miR-212 and PEA15.

FASEB J, 2018
Huang Q, Voloudakis G, Ren Y, Yoon Y, Zhang E, Kajiwara Y, Shao Z, Xuan Z, Lebedev D, Georgakopoulos A, Robakis NK.   +10 more
europepmc   +1 more source

A genetic screen identifies novel polycomb group genes in Drosophila. [PDF]

Genetics, 2007
Gaytán de Ayala Alonso A, Gutiérrez L, Fritsch C, Papp B, Beuchle D, Müller J.   +5 more
europepmc   +1 more source

Acute blast injury reduces brain abeta in two rodent species. [PDF]

Front Neurol, 2012
De Gasperi R, Gama Sosa MA, Kim SH, Steele JW, Shaughness MC, Maudlin-Jeronimo E, Hall AA, Dekosky ST, McCarron RM, Nambiar MP, Gandy S, Ahlers ST, Elder GA.   +12 more
europepmc   +1 more source

Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability.

J Biol Chem, 2005
Serban G, Kouchi Z, Baki L, Georgakopoulos A, Litterst CM, Shioi J, Robakis NK.   +6 more
europepmc   +1 more source

A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk. [PDF]

Cell, 2008
Dreses-Werringloer U, Lambert JC, Vingtdeux V, Zhao H, Vais H, Siebert A, Jain A, Koppel J, Rovelet-Lecrux A, Hannequin D, Pasquier F, Galimberti D, Scarpini E, Mann D, Lendon C, Campion D, Amouyel P, Davies P, Foskett JK, Campagne F, Marambaud P.   +20 more
europepmc   +1 more source

PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations. [PDF]

EMBO J, 2004
Baki L, Shioi J, Wen P, Shao Z, Schwarzman A, Gama-Sosa M, Neve R, Robakis NK.   +7 more
europepmc   +1 more source

Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor.

J Biol Chem, 2007
Litterst C, Georgakopoulos A, Shioi J, Ghersi E, Wisniewski T, Wang R, Ludwig A, Robakis NK.   +7 more
europepmc   +1 more source