Results 221 to 230 of about 366,702 (296)

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

open access: yesAdvanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao   +6 more
wiley   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

open access: yesAdvanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo   +19 more
wiley   +1 more source

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion. [PDF]

open access: yesInt J Oncol
Gao J   +9 more
europepmc   +1 more source

Device to Circuit Co‐Design Utilizing High‐Performance PEALD Indium‐Gallium‐Zinc Oxide Thin‐Film Transistor Enabling Technology Node Scaling in Monolithic 3D Systems

open access: yesAdvanced Science, EarlyView.
This article presents a holistic investigation of M3D‐compatible oxide semiconductor technology using PEALD‐fabricated IGZO TFTs, spanning device‐level characterization, TCAD Modeling, circuit design, and scaled‐node projections. It demonstrates high field‐effect mobility (up to 116.35 cm2 V−1·s−1), robust reliability (△VTH < 0.15 V), low variation ...
Wenhui Wang   +11 more
wiley   +1 more source

Single‐Position Peptide Clustering for Peptidomics Reveals Novel Disease Biomarkers and Dysregulated Proteolytic Characteristics

open access: yesAdvanced Science, EarlyView.
A novel amino acid (aa)‐score‐based single‐position peptide clustering strategy is developed for peptidomics, enabling precise profiling of protein proteolysis in plasma from β‐thalassemia cohort. The method identifies new aa position‐based peptide cluster biomarkers validated by heavy‐labeled peptides, visualizes aggregated changes, uncovers disease ...
Na Li   +13 more
wiley   +1 more source

Nonconventional near-infrared room-temperature phosphorescent materials based on spiropolymer alloy. [PDF]

open access: yesNat Commun
Ren Y   +13 more
europepmc   +1 more source

Heavy Prussian Blue Analog with Magnetic Ordering above 400 K

open access: yesAdvanced Science, EarlyView.
A cyanido‐bridged vanadium(II)–hexacyanomolybdate(III) Prussian Blue analog synthesized mechanochemically exhibits ferrimagnetic ordering above 400 K. SQUID magnetometry and XMCD experiments confirm antiparallel alignment of V and Mo moments. This establishes hexacyanomolybdate(III) as a robust precursor for high‐temperature molecule‐based magnets ...
Michał Magott   +8 more
wiley   +1 more source

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