Results 71 to 80 of about 423,405 (371)

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

open access: yesFEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang   +7 more
wiley   +1 more source

Documentation: International Legal Human Rights Framework -- Human Rights and the Institutionalisation of ASEAN: An Ambiguous Relationship

open access: yesJournal of Current Southeast Asian Affairs, 2014
While the ASEAN Charter of 2007 heralded an era of improved democracy, human rights protection and good governance in accordance with the rule of law, the reality on the ground tells a different story.
Theodor Rathgeber
doaj  

Regulation of Hemichannels and Gap Junction Channels by Cytokines in Antigen-Presenting Cells

open access: yesMediators of Inflammation, 2014
Autocrine and paracrine signals coordinate responses of several cell types of the immune system that provide efficient protection against different challenges.
Pablo J. Sáez   +3 more
doaj   +1 more source

From Center-Vortex Ensembles to the Confining Flux Tube

open access: yesUniverse, 2021
In this review, we discuss the present status of the description of confining flux tubes in SU(N) pure Yang–Mills theory in terms of ensembles of percolating center vortices.
David R. Junior   +2 more
doaj   +1 more source

Discovery of kilogauss magnetic fields on the nearby white dwarfs WD1105-340 and WD2150+591 [PDF]

open access: yesA&A 623, A46 (2019), 2019
Magnetic fields are present in roughly 10% of white dwarfs. These fields affect the structure and evolution of such stars, and may provide clues about their earlier evolution history. Particularly important for statistical studies is the collection of high-precision spectropolarimetric observations of (1) complete magnitude-limited samples and (2 ...
arxiv   +1 more source

Enhancing transporter activity in heterologous expression systems with SAHA: a 2500‐times more potent and odorless alternative to butyrate

open access: yesFEBS Open Bio, EarlyView.
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel   +4 more
wiley   +1 more source

The Limits and Potential of Liberal Democratisation in Southeast Asia

open access: yesJournal of Current Southeast Asian Affairs, 2014
This article argues that Southeast Asia is a region where uneven political development presents a theoretical challenge to the study of regime change and continuity in the academic field of comparative politics.
Sorpong Peou
doaj  

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Evaluating Competing “Democratic” Discourses: The Impact on Human Rights Protection in Southeast Asia

open access: yesJournal of Current Southeast Asian Affairs, 2014
This paper evaluates the impact of competing “democratic” discourses on human rights protection in Southeast Asia. The authors identify three key discourses emanating from a set of national governmental policies, advocacy positions promoted by both ...
James Gomez, Robin Ramcharan
doaj  

Operator independent reliability of direct augmented reality navigated pedicle screw placement and rod bending

open access: yesNorth American Spine Society Journal, 2021
Background: AR based navigation of spine surgeries may not only provide accurate surgical execution but also operator independency by compensating for potential skill deficits.
Mazda Farshad   +7 more
doaj  

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