Results 1 to 10 of about 1,409 (115)

The precision bronchodilator therapy in airflow limitation with asthma defining reversibility: An appraisal through pharmaco-responsiveness-based real-world observation [PDF]

Lung India
Background: The advent of glycopyrronium responsiveness (GPR) has opened an avenue for precision bronchodilator therapy in asthmatics. Methods: We noted 2-Chair test (2CT) and spirometry with salbutamol bronchodilator-responsiveness (BDR) followed ...
Parthasarathi Bhattacharyya, Srijita Sen, Shuvam Ghosh, Avishek Kar   +3 more
doaj   +2 more sources

Epidemiological characteristics and clinical predictors of neonatal jaundice in a multi- ethnic population in Xinjiang, China: a retrospective study [PDF]

Frontiers in Public Health
BackgroundNeonatal jaundice is one of the most common conditions leading to neonatal hospitalization and is a preventable cause of bilirubin-induced neurological dysfunction.ObjectivesThis study aimed to characterize the clinical profile of neonates with
Junyi Wang, Qin Lu, Jin Ma, Shifang Liu, Patigul Ablet, Chuanfu Qin   +5 more
doaj   +2 more sources

Probiotic-Mediated Vitamin D Supplementation Improves the Gut Microbiota and Vitamin D Receptor Composition in Obese Rats. [PDF]

Food Sci Nutr
Lifestyle factors such as regular physical activity, dietary fiber intake, Mediterranean‐style eating patterns, and breastfeeding support gut microbiota balance, whereas Western‐style diets, fast‐food consumption, sugar‐sweetened beverages, and excessive screen time contribute to dysbiosis and obesity.
Kılınç GE, Söğüt MÜ.
europepmc   +2 more sources

Impact of dynapenia, presarcopenia and sarcopenia in chronic obstructive pulmonary disease: a prospective cohort study [PDF]

BMJ Open Respiratory Research
Background Reduced muscle strength and decreased muscle mass (sarcopenia) are known predictors of poor prognosis in chronic obstructive pulmonary disease (COPD).
Chong-Jen Yu, Shih-Yu Chen, Jung-Yien Chien, I-Ling Ya, Pey-Rong Chen, Hui-Chuan Peng, Hui-Ya Liao   +6 more
doaj   +2 more sources

Valiltramiprosate/ALZ‐801 Prevents Hippocampal Atrophy and Clinical Decline in a Stage 2 AD Subpopulation in APOLLOE4 Phase 3 Study [PDF]

Alzheimers Dement
Abstract Background The central hallmark of Alzheimer's disease (AD) is progressive brain atrophy accompanied by amyloid and tau pathologies. Valiltramiprosate is an oral, small‐molecule inhibitor of amyloid oligomer formation in development as a disease‐modifying treatment for AD. Whereas APOLLOE4 did not meet the primary endpoint of cognitive slowing
Yu J, Geerts H, Short S, Schaefer J, Abushakra S, Power A, Tolar M, Hey J.   +7 more
europepmc   +2 more sources

Prevalence of high-risk plasma p-tau217 levels and 5-year transition of risk status in 70-year-olds. [PDF]

Alzheimers Dement
Abstract INTRODUCTION High‐risk plasma p‐tau217 levels predict amyloid‐β pathology in Alzheimer's disease, but little is known about the prevalence and temporal dynamics in the general population. METHODS Participants from the Gothenburg H70 Birth Cohort Study in Sweden were examined (n = 1157) and re‐examined after 5–7 years (n = 771).
Dittrich A, Arslan B, Skillbäck T, Rydén L, Kvartsberg H, Gobom J, Blennow K, Zetterberg H, Kern S, Skoog I.   +9 more
europepmc   +2 more sources

Burden of knee osteoarthritis in China and globally: 1990–2045 [PDF]

BMC Musculoskeletal Disorders
Background Knee osteoarthritis (KOA) is a major global health challenge, with rising prevalence, incidence, and disability-adjusted life years (DALYs).
Mingyang Li, Qilin Xia, Qilong Nie, Ling Ding, Zhen Huang, Zeping Jiang   +5 more
doaj   +2 more sources

Ultrasound-Guided Transperineal Versus Transrectal Prostate Aspiration Biopsy in Diagnosing Prostate Cancer: An Observational Comparison Study. [PDF]

J Ultrasound Med
Background Ultrasound‐guided prostate biopsy is the standard method for the diagnosis of prostate cancer. However, the effect of the optimal puncture approach on diagnostic yield and patient outcomes remains controversial. Objective To compare the diagnostic effectiveness and clinical outcomes of ultrasound‐guided transperineal versus transrectal ...
Cao Y, Zhu H, Wu J.
europepmc   +2 more sources

Optimizing irrigation and nitrogen application strategies to improve sunflower yield and resource use efficiency in a cold and arid oasis region of Northwest China [PDF]

Frontiers in Plant Science
In arid regions, water scarcity, land degradation and groundwater pollution caused by excessive fertilization are the main constraints to sustainable agricultural production. Optimizing irrigation and fertilizer management regime is an effective means of
Xietian Chen, Xietian Chen, Hengjia Zhang, Hengjia Zhang, Shouchao Yu, Chenli Zhou, Anguo Teng, Lian Lei, Yuchun Ba, Fuqiang Li   +9 more
doaj   +2 more sources

Alkali Metal Cations Impact the Selectivity of Radical-Mediated Electrochemical C─H Chlorination. [PDF]

Angew Chem Int Ed Engl
In this work, we found that alkali metal cations in the electrolyte can impact the *Cl binding energy, which controls selectivity between radical‐mediated electrochemical C─H chlorination and competing Cl2 formation. Abstract Electrochemistry offers a promising route toward facilitating organic transformation reactions in a sustainable manner. However,
Wu B, Lu R, Yuan T, Cai B, Wang B, Zhao B, Xi S, Wang Z, Lum Y.   +8 more
europepmc   +2 more sources