Results 81 to 90 of about 69,728 (210)

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Adaptive Conductive Systems: Enabling Deformable Electronics Through Engineered Materials, Circuits, and Intelligent Systems

Advanced Science, EarlyView.
This review presents the research advances of adaptive conductive systems from the perspective of materials, circuits, systems, and applications. Deformable conductors consist of substrates/matrices and conductive materials, structural design of circuit interconnections, fabrication of circuit interconnections, as well as intelligent systems ...
Yufei Lu, Siyu Liang, Jingyi Niu, Jie Chen, Shuo Zhang, Hongjian Zhang, Dongsheng Jia, Wei Huang   +7 more
wiley   +1 more source

Cultural Ecology: Contemporary Understanding of the Relationship between Humans and the Environment

Journal of Landscape Ecology, 2012
The paper explains the concept of contemporary cultural ecology, a scientific approach reflecting the relationship between human society and natural environment.
Lapka Miloslav, Vávra Jan, Sokolíčková Zdenka   +2 more
doaj   +1 more source

Dual‐Functional Terahertz Manipulation of EuBa2Cu3O7 Superconductors via Cooper Pair Dynamics

Advanced Science, EarlyView.
We use a spintronic‐metasurface THz emitter to realize chiral THz generation. Using polarization‐tunable THz pulses, we investigate equilibrium and photoinduced THz responses in a 43 nm thick EuBa2Cu3O7 (EBCO) thin film. The EBCO film achieves 46.81 dB EMI shielding and 113% photoinduced THz modulation with 19.0 ps recovery, enabled by Cooper‐pair ...
Zhangshun Li, Meng Yang, Zuanming Jin, Junxue Li, Zhiqiang Lan, Chen Huang, Alexei V. Balakin, Alexander P. Shkurinov, Yan Peng, Yiming Zhu, Songlin Zhuang   +10 more
wiley   +1 more source

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

Advanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho, Jinsook Ahn, Jimin Yang, Dong Sun Lee, Gahi Hong, Sangkyu Lee, Ho Min Kim   +6 more
wiley   +1 more source

Clean Cut (adaptive, multimodal surgical infection prevention programme) for low‐resource settings: a prospective quality improvement study

BJS (British Journal of Surgery), EarlyView., 2020
Clean Cut is a multimodal, adaptive, checklist‐based infection prevention programme designed to improve compliance with six critical perioperative infection prevention practices. After introducing the programme at five hospitals in Ethiopia, compliance with critical infection prevention standards significantly improved and the relative risk of ...
J. A. Forrester, N. Starr, T. Negussie, D. Schaps, M. Adem, S. Alemu, D. Amenu, N. Gebeyehu, T. Habteyohannes, F. Jiru, A. Tesfaye, E. Wayessa, R. Chen, A. Trickey, S. Bitew, A. Bekele, T. G. Weiser   +16 more
wiley   +1 more source

Grain‐Boundary‐Enriched Cocatalyst Coupled With CuSCN Hole Transport Layer for Efficient Solar Water Oxidation in BiVO4 Photoanode

Advanced Science, EarlyView.
A grain‐boundary‐enriched NiFe cocatalyst is coupled with a CuSCN hole transport layer on BiVO4 photoanodes. The integrated architecture promotes hole extraction, interfacial charge transfer, and surface OER kinetics, highlighting cocatalyst microstructure regulation as a complementary strategy to hole transport layer engineering. ABSTRACT Solar‐driven
Wei Zhao, Yaorong He, Xiao Wang, Lin Zhu, Tong Su, Yujie Zhou, Xiang Li, Peiyao Du, Xiaoquan Lu   +8 more
wiley   +1 more source

A Cross-sectional Study for Examining Catastrophic Healthcare Expenditure Across Socio-demographic Variables among Employees in a Sedentary Occupation

Indian Journal of Community Medicine
Health expenditure above a certain threshold level can result in a financial catastrophe by reducing the expenses on necessities. Certain socio-demographic variables have been observed to play a role in influencing catastrophic healthcare expenditure ...
Monika Yadav, Viji Bathirasamy
doaj   +1 more source

Modulation of the TGF‐β/Smad Signaling Pathway by a Bioactive Oxidized Polygonati Rhizoma Polysaccharide Crosslinked Chitosan Hydrogel as Therapeutic Carrier for Parkinson's Disease Treatment

Advanced Science, EarlyView.
An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai, Jikuang Zhao, Chang Xue, Kailei Xu, Liang Yong, Zhuangwei Zhang, Yi Huang, Jianwei Shuai, Xianzhen Chen, Sheng Nie, Junpeng Xu   +10 more
wiley   +1 more source

Gold Clusters With Open‐Shell Ligands: Superatom Mediated Magnetic Interaction

Angewandte Chemie, EarlyView.
Open‐shell verdazyl radicals were covalently integrated with atomically precise Ir‐doped Au12 (Ir@Au12) superatoms. The resulting radical–superatom hybrids exhibit photoinduced electron transfer, spin delocalization onto the metal‐cluster core, and weak ferromagnetic communication between radicals mediated by the superatomic electronic structure ...
Katsuya Mutoh, Kosei Hayashi, Yoichi Kobayashi, Kazunobu Sato, Rika Tanaka, Daichi Kitagawa, Tatsuya Tsukuda, Takuya Nakashima   +7 more
wiley   +2 more sources