Results 81 to 90 of about 63,023 (238)

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Usefulness of social tagging in organizing and providing access to the web: An analysis of indexing consistency and quality [PDF]

, 2011
This dissertation research points out major challenging problems with current Knowledge Organization (KO) systems, such as subject gateways or web directories: (1) the current systems use traditional knowledge organization systems based on controlled ...
Choi, Yunseon
core  

Parental perceptions of facilitators and barriers to physical activity for children with intellectual disabilities: A mixed methods systematic review [PDF]

, 2018
Background: There is a need increase our understanding of what factors affect physical activity participation in children with intellectual disabilities (ID) and develop effective methods to overcome barriers and increase activity levels.
McGarty, Arlene M., Melville, Craig A.
core   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

Gestational risk factors and birth weight

Revista Ciência em Extensão, 2010
The aim of the present work was to investigate gestational risk factors and their relation to the birth weight of a child in two groups of gestational women who belong to different income levels.
Luiza Cristina Godim Domingues Dias, Nelson Souza   +1 more
doaj  

Observatoire du dépôt légal : reflet de l\u27édition contemporaine - données 2015 [PDF]

Synthèse des tendances observées par la BnF, l\u27Observatoire du dépôt légal est complété d\u27un focus sur les auteurs. Les chiffres et analyses dont disposent la BnF sont accessibles à tous aujourd\u27hui dans l\u27objectif d\u27ouverture des données ...
Bibliothèque nationale de France
core  

Utilization of Historical Site Media by Teachers in Building Student Character in Junior and Senior High Schools in the Central Amanuban Sub-District [PDF]

This community service activity aims to explore the positive impact of using historical site media in an educational context, with a focus on student character development.
Madu, Aleksius, Taneo, Malkisedek, Utomo, Susilo Setyo   +2 more
core   +2 more sources

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

Clean Cut (adaptive, multimodal surgical infection prevention programme) for low‐resource settings: a prospective quality improvement study

BJS (British Journal of Surgery), EarlyView., 2020
Clean Cut is a multimodal, adaptive, checklist‐based infection prevention programme designed to improve compliance with six critical perioperative infection prevention practices. After introducing the programme at five hospitals in Ethiopia, compliance with critical infection prevention standards significantly improved and the relative risk of ...
J. A. Forrester, N. Starr, T. Negussie, D. Schaps, M. Adem, S. Alemu, D. Amenu, N. Gebeyehu, T. Habteyohannes, F. Jiru, A. Tesfaye, E. Wayessa, R. Chen, A. Trickey, S. Bitew, A. Bekele, T. G. Weiser   +16 more
wiley   +1 more source

Primary hyperaldosteronism. Mechanisms and consequences of pathological influence on an organism (review of literature)

Mìžnarodnij Endokrinologìčnij Žurnal, 2019
The work is based on the analysis of world literature data on primary hyperaldosteronism. The data on mechanisms of pathological influences of excessive autonomous aldosterone secretion on the body systems are given.
V.А. Shidlovsky, А.V. Shidlovsky, V.V. Kravtsiv   +2 more
doaj   +1 more source