Results 21 to 30 of about 60,537 (309)

The Pore-Forming α-Toxin from Clostridium septicum Activates the MAPK Pathway in a Ras-c-Raf-Dependent and Independent Manner

Toxins, 2015
Clostridium septicum is the causative agent of atraumatic gas gangrene, with α-toxin, an extracellular pore-forming toxin, essential for disease. How C. septicum modulates the host’s innate immune response is poorly defined, although α-toxin-intoxicated
Anjana Chakravorty, Milena M. Awad, Jackie K. Cheung, Thomas J. Hiscox, Dena Lyras, Julian I. Rood   +5 more
doaj   +1 more source

Crystallisation and Preliminary Crystallographic Analysis of Helicobacter pylori Periplasmic Binding Protein YckK

Crystals, 2017
Helicobacter pylori infection can lead to the development of gastric and duodenal ulcers and gastric cancer. In recent years, the efficacy of the standard therapy has been falling, necessitating ongoing efforts to identify new drug targets.
Mohammad Mizanur Rahman, Daniel Phillip Germantsis, Mayra Alejandra Machuca, Abu Iftiaf Salah Ud-Din, Anna Roujeinikova   +4 more
doaj   +1 more source

Relationship between Central Corneal Thickness and Endothelial Cell Density in Individuals with Primary Glaucoma and the General Population Living at High Altitudes

Journal of Current Ophthalmology
Purpose: To evaluate the impact of high-altitude living on central corneal thickness (CCT) and corneal endothelial cell density (ECD) in individuals diagnosed with primary glaucoma, compared to age-matched healthy controls.
Robin Debbarma, Vinod Sharma, Vinay Gupta, Bhavya Mehta, Pooja Badgujar, Rahul Bhargava   +5 more
doaj   +1 more source

Coordination Polymers of Small Cyano Anions

CHIMIA, 2013
Small cyano anions, and their derivatives, have proved to be remarkably versatile building blocks for coordination polymers. They have led to magnetically ordered materials, structures with new entangled motifs or novel topologies, and a ...
Stuart R. Batten, Glen B. Deacon, Keith S. Murray, David R. Turner   +3 more
doaj   +1 more source

The Methyltransferase DOT1L Controls Activation and Lineage Integrity in CD4+ T Cells during Infection and Inflammation

Cell Reports, 2020
Summary: CD4+ T helper (Th) cell differentiation is controlled by lineage-specific expression of transcription factors and effector proteins, as well as silencing of lineage-promiscuous genes.
Sebastian Scheer, Jessica Runting, Michael Bramhall, Brendan Russ, Aidil Zaini, Jessie Ellemor, Grace Rodrigues, Judy Ng, Colby Zaph   +8 more
doaj   +1 more source

Identification of novel neutralizing determinants for protection against HCV

Hepatology, EarlyView., 2022
Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua, Anne F. Pihl, Anna Offersgaard, Rodrigo Velázquez‐Moctezuma, Carlos R. Duarte Hernandez, Elias H. Augestad, Ulrik Fahnøe, Christian K. Mathiesen, Henrik Krarup, Mansun Law, Jannick Prentoe, Jens Bukh, Judith M. Gottwein   +12 more
wiley   +1 more source

Increasing hypoxia progressively slows early embryonic development in an oviparous reptile, the green turtle, Chelonia mydas

Royal Society Open Science, 2022
Green turtle (Chelonia mydas) embryos are in an arrested state of development when the eggs are laid, but in the presence of oxygen, arrest is broken and development resumes within 12–16 h.
David M. Adams, Sean A. Williamson, Roger G. Evans, Richard D. Reina   +3 more
doaj   +1 more source

Effect of oxygen plasma treatment on the nanofiltration performance of reduced graphene oxide/cellulose nanofiber composite membranes

Green Chemical Engineering, 2021
Graphene based nanosheets have been widely used as building blocks for fabrication of superior separation membrane for water processing. In particular, membranes made of reduced graphene oxide (rGO) show better stability compared with graphene oxide (GO).
Shabin Mohammed, Hanaa M. Hegab, Ranwen Ou, Shasha Liu, Hongyu Ma, Xiaofang Chen, Tam Sridhar, Huanting Wang   +7 more
doaj   +1 more source

Tuning Separator Chemistry: Improving Zn Anode Compatibility via Functionalized Chitin Nanofibers

Advanced Functional Materials, EarlyView.
Nanochitin derived from waste shrimp shells is used to fabricate separators for aqueous zinc batteries. By tuning the density of amine and carboxylic surface groups, water mobility at the separator interface is controlled, promoting uniform zinc deposition, suppressing dendrite growth, and enabling exceptional cycling stability exceeding 2000 h ...
Ibrahim Al Kathemi, Vishnu Arumughan, Mohamed Zbiri, Marcel Kröger, Ira Smal, Eero Kontturi, Roza Bouchal   +6 more
wiley   +1 more source

Understanding the Aerodynamic Benefits of Drafting in the Wake of Cyclists

Proceedings, 2020
A new approach is presented to characterize the aerodynamic benefit from riding in the wake of another cyclist at different downstream locations. The method presented uses the dynamic pressure deficit in the wake of a cycling mannequin to estimate ...
Christopher Brown, Timothy Crouch, David Burton, Mark C. Thompson   +3 more
doaj   +1 more source