Learned Conformational Space and Pharmacophore Into Molecular Foundational Model
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang +8 more
wiley +1 more source
ANTARCTIC DESTINIES: SCOTT, SHACKLETON AND THE CHANGING FACE OF HEROISM. Stephanie Barczewski. 2007. London: Hambledon Continuum. 390 p, illustrated, hard cover. ISBN 978 1 84725 192 3. $28.95/ £25 [PDF]
Janice Cavell
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Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro +6 more
wiley +1 more source
Observations of 3C33, 61{middle dot}1, 379{middle dot}1 and 390{middle dot}3 at 5 GHz with the 5-km Radio Telescope [PDF]
P. J. Hargrave, M. McEllin
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Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
Erratum : « Directive clinique N° 390-Classification et prise en charge de l'hyperplasie de l'endomètre » [Journal of Obstetrics and Gynaecology Canada 41/12 (2019) 1801–1813] [PDF]
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Recent Advances in Mediator and Proton Relay Usage in Molecular Catalysis
The use of electron–proton transfer mediators, redox mediators, and proton relays in synergy with molecular catalysts in energy‐related small‐molecule and organic transformations is discussed, with a focus on recent advances. Linear free‐energy relationship and catalytic Tafel plots provide a systematic foundation for benchmarking these catalytic ...
Yu‐Lin Chi +3 more
wiley +1 more source
Ultrahigh‐Efficiency Dual‐Band Thin‐Film Lithium Niobate Modulator Incorporating Low‐k Underfill for 390 Gbit s−1 PAM8 Transmission [PDF]
Hao Liu +10 more
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New ideas need new space [PDF]
We develop a setting with weak intellectual property rights, where firms' boundaries, location and knowledge spillovers are endogenous. We have two main results.
Diego Rodríguez
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