Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa +3 more
wiley +1 more source
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee +4 more
wiley +1 more source
Design, Synthesis, and Evaluation of Novel Adenine-Based Hydrazones as Potential Anticancer Agents: Cytotoxicity Against A549 and MRC-5 Cell Lines with In Silico Insights. [PDF]
Menteşe E +3 more
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Solvent-controlled Rh-catalysed hydrodehalogenation and construction of phenanthridinone skeleton from a common precursor in one-step sequence and the antitumor activity of its derivatives. [PDF]
Hu DX +5 more
europepmc +1 more source
Absolute Proper Motions of 3c 345, 3c 351, 3c 446, and MSH 14-121
openaire +1 more source
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur +5 more
wiley +1 more source
Deciphering Concentration and Backbone Identity Effects on the Redox Properties of Phthalimide-Based Polymers. [PDF]
Mohanty KT +7 more
europepmc +1 more source
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt +8 more
wiley +1 more source
The Great Divergence Turning into the Great Convergence and Beyond Greif, Avner, Joel Mokyr, Guido Tabellini. 2025. Two Paths to Prosperity: Culture and Institutions in Europe and China, 1000–2000. Princeton & Oxford: Princeton University Press, 533. [PDF]
Boris BEGOVIĆ
doaj

