Results 41 to 50 of about 1,390,247 (199)

Transport evidence of mass-less Dirac fermions in (Cd1−x−yZnxMny)3As2 (x + y = 0.4)

Materials Research Express, 2020
Charge carriers parameters on a 2D-layer surface for (Cd _1−x−y Zn _x Mn _y ) _3 As _2 ( y  = 0.08) (the concentration ${n}_{2D}$  = 1.9 × 10 ^12 cm ^–2 , the effective value of the 2D-layer ${d}_{2D}={n}_{2D}/{n}_{3D}$  = 14.5 nm, the wave vector ${k}_ ...
V S Zakhvalinskii, T B Nikulicheva, E A Pilyuk, E Lähderanta, M A Shakhov, O N Ivanov, E P Kochura, A V Kochura, B A Aronzon   +8 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Cardinality enrichment of 3-D FCC-MDW code in wavelength/time/space domains for non-coherent OCDMA at 17 Gbps with interference suppression En/Decoder

Results in Optics
This paper introduces a new Interference Suppression Scheme (ISS) for wavelength/time/spatial Optical Code Division Multiple Access (OCDMA) systems, demonstrated through a new 3-D FCC-MDW coding architecture. The 3-D FCC-MDW code offers flexible in-phase
A.J. Rupok, C.B.M. Rashidi, K.N.F.Ku Azir, B. Nakarmi, Mohammad Nayeem Morshed   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Biomechanics of the lead straight punch of different level boxers

Frontiers in Physiology, 2022
We analyze and compare the differences in the biomechanical parameters between the lead straight punch and the index of force development of the lower extremities of boxers of different levels of ability.
Yang Liu, Yang Liu, Yang Liu, Yang Liu, Zhiqiang Zhu, Xiuxiu Chen, Chengyuan Deng, Xiujie Ma, Xiujie Ma, Bin Zhao, Bin Zhao, Bin Zhao   +11 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Optimizing process parameters of ultrasonic vibration assisted grinding CFRP based on response surface method

Jin'gangshi yu moliao moju gongcheng, 2022
To solve the contradiction between high quality and high efficiency of CFRP machining surface, the quadratic regression models of 3D surface roughness Sa and surface damage layer depth Dd were established by using the response surface method, and the ...
Daohang JI, Yan CHEN, Nan GUO, Yuhong LIANG, Junjie JI, Yongqing WANG   +5 more
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source