Results 71 to 80 of about 2,709,443 (248)

Three dimensional topological field theories and Nahm sum formulas

open access: yesSciPost Physics
It is known that a large class of characters of 2d conformal field theories (CFTs) can be written in the form of a Nahm sum. In [D. Zagier, in Frontiers in number theory, physics, and geometry II, Springer, Berlin (2007)], D.
Dongmin Gang, Heeyeon Kim, Byoungyoon Park, Spencer Stubbs
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Critical exponents of finite temperature chiral phase transition in soft-wall AdS/QCD models

open access: yesJournal of High Energy Physics, 2019
Criticality of chiral phase transition at finite temperature is investigated in a soft-wall AdS/QCD model, with two, three degenerate flavors (N f = 2, 3) and two light plus one heavier flavor (N f = 2 + 1).
Jianwei Chen   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The fermion–boson map for large d

open access: yesNuclear Physics B, 2019
We show that the three-dimensional map between fermions and bosons at finite temperature generalises for all odd dimensions d>3. We further argue that such a map has a nontrivial large d limit.
Evangelos G. Filothodoros   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

d-magnetism instability in R-Co intermetallic compounds

open access: yesJournal of Science: Advanced Materials and Devices, 2016
Magnetic phenomena observed in R-Co intermetallic compounds with the d-magnetism instability are reviewed. The magnetic instability in these compounds is intimately related to the special position of the Fermi level in the hybridized 3d-5d (4d) band near
Irina Yu. Gaidukova, Ashot S. Markosyan
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Anisotropic swim stress in active matter with nematic order

open access: yesNew Journal of Physics, 2018
Active Brownian particles (ABPs) transmit a swim pressure ${{\rm{\Pi }}}^{{\rm{swim}}}=n\zeta {D}^{{\rm{swim}}}$ to the container boundaries, where ζ is the drag coefficient, D ^swim is the swim diffusivity and n is the uniform bulk number density far ...
Wen Yan, John F Brady
doaj   +1 more source

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