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A review of 3D bioprinting for organoids [PDF]

Medical Review
Current two-dimensional (2D) cell models for effective drug screening suffer from significant limitations imposed by the lack of realism in the physiological environment. Three-dimensional (3D) organoids models hold immense potential in mimicking the key
Li Zeqing, Chen Long, Wu Jialin, Chen Yikang, Zhu Yizhun, Li Gang, Xie Guoxi, Tang Guosheng, Xie Maobin   +8 more
doaj   +2 more sources

Advances of 3D bioprinting technology for periodontal tissue regeneration [PDF]

iScience
Summary: 3D bioprinting technology for periodontal tissue regeneration is an advanced manufacturing technique that utilizes three-dimensional (3D) printing principles to fabricate intricate, viable structures that are specifically devised to meet with ...
Huanhuan Chen, Yu Wang, Yue Lai, Chenda Meng, Xiner Ning, Tianmin Xu, Guangying Song, Yunfan Zhang, Yifan Lin, Bing Han   +9 more
doaj   +2 more sources

3D bioprinting bone/cartilage organoids: construction, applications, and challenges [PDF]

Journal of Orthopaedic Translation
Orthopaedic disorders, such as osteoporosis and osteoarthritis, impose substantial suffering upon an increasing population, driving demand for accurate disease models.
Deju Gao, Ruipeng Li, Jie Pan, Cairong Li, Wei Zhang, Ling Qin, Yuxiao Lai   +6 more
doaj   +2 more sources

3D bioprinting and mesenchymal stem cells: A bibliometric analysis of emerging trends and advancements. [PDF]

Cell Transplant
Li YC, Shao B, Ye K, Liu X, Wang HD, Sun CL, Xiao YY, Wang H.   +7 more
europepmc   +2 more sources

Automated detection and growth tracking of 3D bio-printed organoid clusters using optical coherence tomography with deep convolutional neural networks

Frontiers in Bioengineering and Biotechnology, 2023
Organoids are advancing the development of accurate prediction of drug efficacy and toxicity in vitro. These advancements are attributed to the ability of organoids to recapitulate key structural and functional features of organs and parent tumor ...
Di Bao, Ling Wang, Ling Wang, Xiaofei Zhou, Xiaofei Zhou, Shanshan Yang, Shanshan Yang, Kangxin He, Mingen Xu, Mingen Xu   +9 more
doaj   +1 more source

Articular Cartilage Regeneration through Bioassembling Spherical Micro-Cartilage Building Blocks

Cells, 2022
Articular cartilage lesions are prevalent and affect one out of seven American adults and many young patients. Cartilage is not capable of regeneration on its own.
Brian E. Grottkau, Zhixin Hui, Yonggang Pang   +2 more
doaj   +1 more source

High throughput 3D gel-based neural organotypic model for cellular assays using fluorescence biosensors

Communications Biology, 2022
Fibrin gel-based 3D co-culture models with human-iPSC differentiated dopaminergic or glutamatergic neurons and astrocytes are shown to be functional using biosensors and can be scaled up for high-throughput assays.
Srikanya Kundu, Molly E. Boutin, Caroline E. Strong, Ty Voss, Marc Ferrer   +4 more
doaj   +1 more source

Design and Implementation of Anatomically Inspired Mesenteric and Intestinal Vascular Patterns for Personalized 3D Bioprinting

Applied Sciences, 2022
Recent progress in bioprinting has made possible the creation of complex 3D intestinal constructs, including vascularized villi. However, for their integration into functional units useful for experimentation or implantation, the next challenge is to ...
Rachel Cadle, Dan Rogozea, Leni Moldovan, Nicanor I. Moldovan   +3 more
doaj   +1 more source

Convergence of 3D Bioprinting and Nanotechnology in Tissue Engineering Scaffolds

Biomimetics, 2023
Three-dimensional (3D) bioprinting has emerged as a promising scaffold fabrication strategy for tissue engineering with excellent control over scaffold geometry and microstructure.
Shike Zhang, Xin Chen, Mengyao Shan, Zijuan Hao, Xiaoyang Zhang, Lingxian Meng, Zhen Zhai, Linlin Zhang, Xuying Liu, Xianghong Wang   +9 more
doaj   +1 more source

Emerging 3D bioprinting applications in plastic surgery

Biomaterials Research, 2023
Plastic surgery is a discipline that uses surgical methods or tissue transplantation to repair, reconstruct and beautify the defects and deformities of human tissues and organs.
Pu Yang, Yikun Ju, Yue Hu, Xiaoyan Xie, Bairong Fang, Lanjie Lei   +5 more
doaj   +1 more source