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Stress‐Adaptive Biomaterials With Tunable Yielding Architectures Regulate Organoid Morphogenesis

Small, Volume 22, Issue 50, 7 September 2026.
Granular hydrogels are developed to tune the yield stress levels at which 3D tissue culture matrices undergo plastic deformation. We use these materials to regulate growth‐induced stresses, with demonstrable effects on cancer spheroid invasion and brain organoid morphogenesis.
James P. W. Reeves, Sabra Rostami, Mostafa Rammal, Andrei Bocan, Paula Lépine, Matthew J. Harrington, Thomas M. Durcan, Christopher Moraes   +7 more
wiley   +1 more source

Tissue and Organ 3D Bioprinting [PDF]

SLAS Technology, 2018
Three-dimensional (3D) bioprinting enables the creation of tissue constructs with heterogeneous compositions and complex architectures. It was initially used for preparing scaffolds for bone tissue engineering. It has recently been adopted to create living tissues, such as cartilage, skin, and heart valve. To facilitate vascularization, hollow channels
Kaiming Ye, Sha Jin
exaly   +3 more sources

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Stereolithography 3D Bioprinting

2020
Stereolithography (SLA) 3D bioprinting has emerged as a prominent bioprinting method addressing the requirements of complex tissue fabrication. This chapter addresses the advancement in SLA 3D bioprinting in concurrent with the development of novel photocrosslinkable biomaterials with enhanced physical and chemical properties.
Hitendra, Kumar, Keekyoung, Kim
openaire   +2 more sources

3D Bioprinting in Otolaryngology: A Review

Advanced Healthcare Materials, 2023
AbstractThe evolution of tissue engineering and 3D bioprinting has allowed for increased opportunities to generate musculoskeletal tissue grafts that can enhance functional and aesthetic outcomes in otolaryngology—head and neck surgery. Despite literature reporting successes in the fabrication of cartilage and bone scaffolds for applications in the ...
Alexandra McMillan, Nadia McMillan, Nikesh Gupta, Sohit P. Kanotra, Aliasger K. Salem   +4 more
openaire   +2 more sources

Nanocomposite bioinks for 3D bioprinting

Acta Biomaterialia, 2022
Three-dimensional (3D) bioprinting is an advanced technology to fabricate artificial 3D tissue constructs containing cells and hydrogels for tissue engineering and regenerative medicine. Nanocomposite reinforcement endows hydrogels with superior properties and tailored functionalities.
Yanli Cai, Soon Yee Chang, Soo Wah Gan, Sha Ma, Wen Feng Lu, Ching-Chiuan Yen   +5 more
openaire   +2 more sources

‘Living’ Inks for 3D Bioprinting

Trends in Biotechnology, 2019
A critical aspect in bioprinting is the formulation of bioactive inks. A recent breakthrough in bioink design (Qian et al. Nano Lett. 2019; https://doi.org/10.1021/acs.nanolett.9b00066) enables the direct writing of catalytically active microorganisms with unprecedented cell loading, tunable structural properties, and long-term activity.
Leo, Hsu, Xiaocheng, Jiang
openaire   +2 more sources

3D Bioprinting of Neural Tissues

Advanced Healthcare Materials, 2020
AbstractThe human nervous system is a remarkably complex physiological network that is inherently challenging to study because of obstacles to acquiring primary samples. Animal models offer powerful alternatives to study nervous system development, diseases, and regenerative processes, however, they are unable to address some species‐specific features ...
Melissa Cadena, Liqun Ning, Alexia King, Boeun Hwang, Linqi Jin, Vahid Serpooshan, Steven A. Sloan   +6 more
openaire   +2 more sources

3D Coaxial Bioprinting of Vasculature

2020
Development of a suitable vascular network for an efficient mass exchange is crucial to generate three-dimensional (3D) viable and functional thick construct in tissue engineering. Different technologies have been reported for the fabrication of vasculature conduits, such as decellularized tissues and biomaterial-based blood vessels.
Yang, Wu, Yahui, Zhang, Yin, Yu, Ibrahim T, Ozbolat   +3 more
openaire   +2 more sources

A FRESH SLATE for 3D bioprinting

Science, 2019
Greater structural complexity has been achieved in additive manufacturing of ...
Queeny, Dasgupta, Lauren D, Black
openaire   +2 more sources

3D Bioprinting and Stem Cells

2018
Three-dimensional (3D) in vitro modeling is increasingly relevant as two-dimensional (2D) cultures have been recognized with limits to recapitulate the complex endogenous conditions in the body. Additionally, fabrication technology is more accessible than ever.
Caitlyn A, Moore, Niloy N, Shah, Caroline P, Smith, Pranela, Rameshwar   +3 more
openaire   +2 more sources