Results 221 to 230 of about 571,399 (301)

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

Advanced Science, EarlyView.
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han, Jianhui Li, Yuting Zhu, Penghui Liu, Yaoyao Zheng, Muchun He, Bo Dong   +6 more
wiley   +1 more source

Design of a low-cost, portable blower-based breath simulator using 3D printing for respiratory research and education. [PDF]

HardwareX
Truong CT, Phan TD, Truong Pham LX, Nguyen HH, Nguyen TT, Duong VT.   +5 more
europepmc   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Digital restoration and feature recognition of a Qing-Dynasty vernacular dwelling based on multimodal data fusion. [PDF]

Sci Rep
Xia X, Chen Z, Xu Y.
europepmc   +1 more source

Characterising Activities in 3D City Modelling [PDF]

, 2020
openaire  

Modern and Ancient Genomes Reveal Neolithic Paternal Expansions of Millet and Rice Farmers and Demic Diffusion from China into Mainland Southeast Asia

Advanced Science, EarlyView.
This study clarifies the genetic patterns of paternal lineages across East Asia and Mainland Southeast Asia. Han populations are relatively homogeneous, whereas southern ethnolinguistic minorities display regional structures. Shared Y‐chromosome lineages indicate Neolithic expansions and extensive north‐south gene flow, supporting demic diffusion ...
Yunhui Liu, Lintao Luo, Yutong Jiang, Minzhu Zhao, Ting Yang, Zhiyong Wang, Lisiteng Luo, Yuhang Feng, Zihao Zhu, Yuzhu Wang, Limei Zhang, Bofeng Zhu, Chao Liu, Renkuan Tang, Mengge Wang, Guanglin He   +15 more
wiley   +1 more source

Radiation Attenuation Calculation of 3D-Printed Polymers Across Variable Infill Densities and Phase Angles for Nuclear Medicine Applications. [PDF]

Polymers (Basel)
Lopez TB, Cabalhug JH, Arriola E, Afable ML, Lorenzo RJW, Fronda GB, Mecarandayo P, Santos GN, Advincula R, Astronomo A, Alvarez MJ.   +10 more
europepmc   +1 more source

Highly detailed 3D modelling of Mayan cultural heritage using an UAV [PDF]

, 2014
De Maeyer, Philippe, De Wulf, Alain, Lonneville, Britt, Nuttens, Timothy, Stal, Cornelis   +4 more
core   +1 more source

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

Advanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang, Shaoju Jin, Shaoying Wen, Wen Zeng, Chen Wang, Jingyu Wang, Qingyun Song, Guizhong Li, Pengzhi Yin, Yuhui Liao, Yuee Chai, Huiping Zhang, Shengchao Ma   +12 more
wiley   +1 more source

Mathematical modeling of combinatorial antigen targeting with multiple CAR T-cell products for glioblastoma treatment. [PDF]

NPJ Syst Biol Appl
Li R, Barish M, Gutova M, Feldman LA, Brown CE, Rockne RC, Cho H.   +6 more
europepmc   +1 more source