Results 61 to 70 of about 116,616 (309)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Towards Rapid Generation and Visualisation of Large 3D Urban Landscapes for Mobile Device Navigation [PDF]
, 2008 In this paper a procedural 3D modelling solution for mobile devices is presented based on scripting algorithms allowing for both the automatic and also semi-automatic creation of photorealistic quality virtual urban content.
Baker, S. +3 more
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
URBANISATION AND 3D SPATIAL MODELLING- A GEOMETRIC APPROACH [PDF]
ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2013 Urbanisation creates immense competition for space, this may be attributed to an increase in population owing to domestic and external tourism. Most cities are constantly exploring all avenues in maximising its limited space.
E. E. Duncan, A. Abdul Rahman
doaj +1 more source
Reverse engineering in construction [PDF]
, 2003 Recently a great deal of research into construction IT has been completed, and this is ongoing to improve efficiency and quality in the construction sector.
Arayici, Y, Hamilton, A, Hunter, G
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Seeing the invisible: from imagined to virtual urban landscapes [PDF]
, 2020 Urban ecosystems consist of infrastructure features working together to provide services for inhabitants. Infrastructure functions akin to an ecosystem, having dynamic relationships and interdependencies.
Gopal, Sucharita +3 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
INTEGRATION BETWEEN SURFACE AND SUBSURFACE SPATIAL OBJECTS FOR DEVELOPING OMAN 3D SDI BASED ON THE CITYGML STANDARD [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019 The paper investigates the capability to integrate the surface and subsurface 3D spatial objects data structure within the 3D spatial data infrastructure (3D SDI) based on the CityGML standards.
K. Al Kalbani, A. Abdul Rahman
doaj +1 more source