Results 71 to 80 of about 3,824,869 (307)

PET imaging of hepatocellular carcinoma with [124I]IV-14

EJNMMI Research
Background Currently, positron emission tomography (PET) plays no clear role in clinical imaging and management of hepatocellular carcinoma (HCC). New radiotracers for new target(s) are needed for PET imaging of HCC. Uridine-cytidine kinase 2 (UCK2) is a
Wei Cao, Olga Sergeeva, William Julian, Adam Kresak, Destiny Lusinger, Joseph Schneider, Marc S. Berridge, Sandra Sexton, Patrick Wojtylak, Qiubai Li, Wendy Liu, Ernest Ricky Chan, Yogen Saunthararajah, Zhenghong Lee   +13 more
doaj   +1 more source

Astrocyte Infection during Rabies Encephalitis Depends on the Virus Strain and Infection Route as Demonstrated by Novel Quantitative 3D Analysis of Cell Tropism

Cells, 2020
Although conventional immunohistochemistry for neurotropic rabies virus (RABV) usually shows high preference for neurons, non-neuronal cells are also potential targets, and abortive astrocyte infection is considered a main trigger of innate immunity in ...
Madlin Potratz, Luca Zaeck, Michael Christen, Verena te Kamp, Antonia Klein, Tobias Nolden, Conrad M. Freuling, Thomas Müller, Stefan Finke   +8 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Deep learning applied to standard radiographs improves detection of implant loosening in total knee arthroplasty: A proof‐of‐concept study

Journal of Experimental Orthopaedics
Purpose Implant loosening is a common cause of failure in total knee arthroplasty, and for appropriate treatment, the correct diagnosis is of vital importance.
Kelly Mills, Guido A. deJong, Simon N. vanLaarhoven, Thomas J. J. Maal, Petra J. C. Heesterbeek   +4 more
doaj   +1 more source

Analyzing 3D Images of the Brain

NeuroImage, 1996
During the past 5 years, there has been a considerable effort of research in automating the analysis and fusion of multidimensional images, yielding important theoretical and practical new results. These results could now be useful to brain research.
openaire   +3 more sources

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

A Data Clustering and Streamline Reduction Method for 3D MR Flow Vector Field Simplification [PDF]

, 2004
With the increasing capability of MR imaging and Computational Fluid Dynamics (CFD) techniques, a significant amount of data related to the haemodynamics of the cardiovascular systems are being generated.
Carmo, Bernardo Silva, Yang, Guang-Zhong, Ng, Y H Pauline, Prügel-Bennett, Adam   +3 more
core   +2 more sources

A Deep-Learning-based 3D Defect Quantitative Inspection System in CC Products Surface

Sensors, 2020
To create an intelligent surface region of interests (ROI) 3D quantitative inspection strategy a reality in the continuous casting (CC) production line, an improved 3D laser image scanning system (3D-LDS) was established based on binocular imaging and ...
Liming Zhao, Fangfang Li, Yi Zhang, Xiaodong Xu, Hong Xiao, Yang Feng   +5 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source